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The present study offers important insights in this area, including: (\n                    <jats:italic>i<\/jats:italic>\n                    ) macrophages can confer protective memory transferrable to na\u00efve hosts; (\n                    <jats:italic>ii<\/jats:italic>\n                    ) SA SSSI can induce memory in bone marrow myeloid precursors; and (\n                    <jats:italic>iii<\/jats:italic>\n                    ) specific memory against recurring SA SSSI is localized and distinct from disseminated infection. These findings will accelerate novel strategies to prevent and treat SA infections.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1808353115","type":"journal-article","created":{"date-parts":[[2018,10,8]],"date-time":"2018-10-08T15:15:33Z","timestamp":1539011733000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":79,"title":["Protective immunity in recurrent\n                    <i>Staphylococcus aureus<\/i>\n                    infection reflects localized immune signatures and macrophage-conferred memory"],"prefix":"10.1073","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2567-4418","authenticated-orcid":false,"given":"Liana C.","family":"Chan","sequence":"first","affiliation":[{"name":"Los Angeles Biomedical Research Institute, Harbor\u2013University of California, Los Angeles Medical Center, Torrance, CA 90502;"},{"name":"Division of Molecular Medicine, Department of Medicine, Harbor\u2013University of 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