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U.S.A."],"published-print":{"date-parts":[[2019,1,29]]},"abstract":"<jats:title>Significance<\/jats:title>\n                  <jats:p>\n                    Virulent phages can reduce populations of bacteria and help shape bacterial evolution. Here, we used three virulent phages to understand their equilibrium with\n                    <jats:italic>V. cholerae<\/jats:italic>\n                    in nutrient-limiting aquatic microcosms. It has been proposed that phages quench cholera outbreaks, but no direct evidence of phage predation in aquatic environments had been established. Here, we show that different phages possess varied abilities to infect in certain niches or stages of the host bacterial life cycle. Unveiling the phage\/bacterial interactions in their natural setting is important to the understanding of cholera outbreaks and could be ultimately used to help develop a method for outbreak prediction and\/or control.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1810138116","type":"journal-article","created":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T20:29:28Z","timestamp":1547238568000},"page":"1627-1632","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":55,"title":["Niche adaptation limits bacteriophage predation of\n                    <i>Vibrio cholerae<\/i>\n                    in a nutrient-poor aquatic environment"],"prefix":"10.1073","volume":"116","author":[{"given":"Cecilia A.","family":"Silva-Valenzuela","sequence":"first","affiliation":[{"name":"Department of Molecular Biology and Microbiology, Tufts University, Boston, MA 02111"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Camilli","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Microbiology, Tufts University, Boston, MA 02111"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2019,1,11]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2013.00375"},{"key":"e_1_3_3_2_2","first-page":"335","article-title":"Presence of vibrios in surface water and their relation with cholera in a community","volume":"36","author":"Khan MU","year":"1984","unstructured":"MU Khan, MD Shahidullah, MS Haque, WU Ahmed, Presence of vibrios in surface water and their relation with cholera in a community. 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