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Among the unique immune factors and embryonic genes associated with cardiac regeneration, we identified Ccl24, which encodes a cytokine, and Igf2bp3, which encodes an RNA-binding protein, as previously unrecognized regulators of cardiomyocyte proliferation. Our data provide insights into the molecular basis of neonatal heart regeneration and identify genes that can be modulated to promote heart regeneration.<\/jats:p>","DOI":"10.1073\/pnas.1905824116","type":"journal-article","created":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T20:55:26Z","timestamp":1566852926000},"page":"18455-18465","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":136,"title":["Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling"],"prefix":"10.1073","volume":"116","author":[{"given":"Zhaoning","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Molecular Biology, Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390;"},{"name":"Senator Paul D. 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