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Our findings suggest that the combination of a dopamine receptor antagonist with radiation enhances the efficacy of RT in GBM by preventing radiation-induced phenotype conversion of radiosensitive non-GICs into treatment-resistant, induced GICs (iGICs).<\/jats:p>","DOI":"10.1073\/pnas.1920154117","type":"journal-article","created":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T20:06:32Z","timestamp":1588363592000},"page":"11085-11096","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":68,"title":["The dopamine receptor antagonist trifluoperazine prevents phenotype conversion and improves survival in mouse models of glioblastoma"],"prefix":"10.1073","volume":"117","author":[{"given":"Kruttika","family":"Bhat","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, CA 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