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Testis formation may be due to inappropriate interaction between the mutated WT1 and an essential ovarian determinant \u03b2-CATENIN. These data show that variants affecting a specific domain of a developmental transcription factor can switch organ fate.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1921676117","type":"journal-article","created":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T19:59:45Z","timestamp":1591214385000},"page":"13680-13688","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":63,"title":["Testis formation in XX individuals resulting from novel pathogenic variants in Wilms\u2019 tumor 1 (\n                    <i>WT1<\/i>\n                    ) gene"],"prefix":"10.1073","volume":"117","author":[{"given":"Caroline","family":"Eozenou","sequence":"first","affiliation":[{"name":"Human Developmental Genetics Unit, Institut Pasteur, 75724 Paris, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitzan","family":"Gonen","sequence":"additional","affiliation":[{"name":"Laboratory of Stem Cell Biology and Developmental 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