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Treg cells exhibit repetitive-scanning motility, which may be important in suppressing Th17 cell effector functions by inhibition of Ca\n                    <jats:sup>2+<\/jats:sup>\n                    signaling and by limiting their access to APCs, thus limiting their reactivation in the spinal cord. These findings will help to understand how Treg cells prevent autoimmunity and dampen immune responses, and how autoimmune diseases can be effectively targeted using Treg-based cellular therapies.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2006895117","type":"journal-article","created":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T20:19:50Z","timestamp":1596140390000},"page":"20088-20099","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":61,"title":["Regulatory T cells suppress Th17 cell Ca\n                    <sup>2+<\/sup>\n                    signaling in the spinal cord during murine autoimmune neuroinflammation"],"prefix":"10.1073","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6832-5547","authenticated-orcid":false,"given":"Shivashankar","family":"Othy","sequence":"first","affiliation":[{"name":"Department of Physiology &amp; Biophysics, University of California, Irvine, CA 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