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These data are significant for our understanding of the origins and maintenance of macrophage subpopulations in both organs; our results point to a fundamental mechanism underpinning male infertility by infection and inflammation, and pave the way for the development of innovative therapeutics to treat this important and common condition.<\/jats:p>","DOI":"10.1073\/pnas.2013686117","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T16:30:50Z","timestamp":1609173050000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":94,"title":["Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis"],"prefix":"10.1073","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4913-5390","authenticated-orcid":false,"given":"Ming","family":"Wang","sequence":"first","affiliation":[{"name":"Medical Research Center, The First Affiliated Hospital of 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