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These parasites have genes that encode homologs of human and plant NSUN2 methyltransferases (m\n                    <jats:sup>5<\/jats:sup>\n                    C \u201cwriters\u201d). We show that one of these homologs, termed PyNSUN2, stabilizes mRNA transcripts in\n                    <jats:italic>P. yoelii<\/jats:italic>\n                    and mediates m\n                    <jats:sup>5<\/jats:sup>\n                    C-associated development of the parasite sexual stages (gametocytes). Further research on m\n                    <jats:sup>5<\/jats:sup>\n                    C and other epitranscriptomic modifications may yield new insights into molecular pathways of gametocyte development and mosquito infectivity that can be exploited to interrupt malaria transmission.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2110713119","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T16:10:15Z","timestamp":1645719015000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":28,"title":["5-methylcytosine modification by\n                    <i>Plasmodium<\/i>\n                    NSUN2 stabilizes mRNA and mediates the development of gametocytes"],"prefix":"10.1073","volume":"119","author":[{"given":"Meng","family":"Liu","sequence":"first","affiliation":[{"name":"Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Orthopaedic Department of 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