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Since the overall structure of EmrE resembles those of other transporters containing inverted repeat domains, our findings have application to other secondary active transporters.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2110790118","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T19:00:29Z","timestamp":1633374029000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":19,"title":["Asymmetric protonation of glutamate residues drives a preferred transport pathway in EmrE"],"prefix":"10.1073","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2334-6456","authenticated-orcid":false,"given":"Jianping","family":"Li","sequence":"first","affiliation":[{"name":"Department of Chemistry, New York University, New York, NY 10003"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ampon","family":"Sae Her","sequence":"additional","affiliation":[{"name":"Department of Chemistry, New York University, New York, NY 10003"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1185-6088","authenticated-orcid":false,"given":"Nathaniel J.","family":"Traaseth","sequence":"additional","affiliation":[{"name":"Department of Chemistry, New York University, New York, NY 10003"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2021,10,4]]},"reference":[{"key":"e_1_3_4_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3380"},{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00461-18"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2008.12.018"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.104.049247"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M408187200"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.12.6856"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10703"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1999"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1708671114"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M602088200"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi050356t"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10858-014-9862-y"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10858-020-00323-z"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10858-012-9676-8"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0709387104"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201303091"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja503145x"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/9780470034590.emrstm1413"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.48909"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1520431113"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.201511404"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1722399115"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1802177115"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/1439-7633(20020703)3:7<604::AID-CBIC604>3.0.CO;2-X"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00305"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.8.5264"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1719187115"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1135406"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0704425104"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2005.12.054"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2010.06.004"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0048-6"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/pro.3355"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.601963"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmra.1996.0022"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1080\/00268979809483251"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.478702"},{"key":"e_1_3_4_38_2","first-page":"473","article-title":"Nmr population-inversion using a composite pulse","volume":"33","author":"Levitt M. 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