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Consistently, transcriptomic profiles of\n                    <jats:italic>Lef1<\/jats:italic>\n                    -ablated chondrocytes exhibited enhanced anabolism, yet impaired pathways related to calcification and inflammation. Accordingly, cartilage mineralization of the lateral joint compartment relies on amplified inflammatory pathways, contributing to articular damage following PTOA.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2116855119","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T14:29:51Z","timestamp":1653056991000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":17,"title":["Lef1 ablation alleviates cartilage mineralization following posttraumatic osteoarthritis induction"],"prefix":"10.1073","volume":"119","author":[{"given":"Jinan","family":"Elayyan","sequence":"first","affiliation":[{"name":"Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, 9112102 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1619-4423","authenticated-orcid":false,"given":"Idan","family":"Carmon","sequence":"additional","affiliation":[{"name":"Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, 9112102 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lital","family":"Zecharyahu","sequence":"additional","affiliation":[{"name":"Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, 9112102 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Batshon","sequence":"additional","affiliation":[{"name":"Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, 9112102 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0421-9144","authenticated-orcid":false,"given":"Yonathan H.","family":"Maatuf","sequence":"additional","affiliation":[{"name":"Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, 9112102 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli","family":"Reich","sequence":"additional","affiliation":[{"name":"Institute of Biomedical and Oral Research, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, 9112102 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1647-0010","authenticated-orcid":false,"given":"Maitena","family":"Dumont","sequence":"additional","affiliation":[{"name":"Koret School of Veterinary Medicine, Robert H. 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