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Our results illustrate that autophagy is required for PMC metabolism and survival necessary to sustain intestinal stem cells and mouse survival, and failure to maintain PMCs through autophagy contributes to IBD.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2202016119","type":"journal-article","created":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T14:58:43Z","timestamp":1652194723000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":18,"title":["Autophagy in PDGFR\u03b1+ mesenchymal cells is essential for intestinal stem cell survival"],"prefix":"10.1073","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8963-658X","authenticated-orcid":false,"given":"Yang","family":"Yang","sequence":"first","affiliation":[{"name":"Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Gomez","sequence":"additional","affiliation":[{"name":"Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903"},{"name":"Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ 08544"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Marsh","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of California, San Francisco, CA 94143"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Poillet-Perez","sequence":"additional","affiliation":[{"name":"Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshada","family":"Sawant","sequence":"additional","affiliation":[{"name":"Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Genetics, Rutgers University, Piscataway, NJ, 08854"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noel R.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, Princeton University, Princeton, NJ 08544"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. 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