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Hence, spin constraints in the oxygen reduction must be considered. Here, we show that the electron transfer efficiency from chiral electrodes to oxygen (oxygen reduction reaction) is enhanced over that from achiral electrodes. We demonstrate lower overpotentials and higher current densities for chiral catalysts versus achiral ones. This finding holds even for electrodes composed of heavy metals with large spin\u2013orbit coupling. The effect results from the spin selectivity conferred on the electron current by the chiral assemblies, the chiral-induced spin selectivity effect.<\/jats:p>","DOI":"10.1073\/pnas.2202650119","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T15:00:31Z","timestamp":1658156431000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":114,"title":["Chirality enhances oxygen reduction"],"prefix":"10.1073","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1170-7362","authenticated-orcid":false,"given":"Yutao","family":"Sang","sequence":"first","affiliation":[{"name":"Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot 76100, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4652-9789","authenticated-orcid":false,"given":"Francesco","family":"Tassinari","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot 76100, Israel"},{"name":"Department of Engineering \u201cEnzo Ferrari,\u201d University of Modena and Reggio Emilia, 41125 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kakali","family":"Santra","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot 76100, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot 76100, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1183-2406","authenticated-orcid":false,"given":"Claudio","family":"Fontanesi","sequence":"additional","affiliation":[{"name":"Department of Engineering \u201cEnzo Ferrari,\u201d University of Modena and Reggio Emilia, 41125 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian P.","family":"Bloom","sequence":"additional","affiliation":[{"name":"Chemistry Department, University of Pittsburgh, Pittsburgh, PA 15260"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H.","family":"Waldeck","sequence":"additional","affiliation":[{"name":"Chemistry Department, University of Pittsburgh, Pittsburgh, PA 15260"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9217-2218","authenticated-orcid":false,"given":"Jonas","family":"Fransson","sequence":"additional","affiliation":[{"name":"Department of Physics and Astronomy, Uppsala University, SE-751 21 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1910-366X","authenticated-orcid":false,"given":"Ron","family":"Naaman","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot 76100, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2022,7,18]]},"reference":[{"key":"e_1_3_4_1_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00488"},{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00462"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr5003563"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.23.12971"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4738"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature11115"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/356301a0"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr950051s"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.2805"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/prot.23022"},{"key":"e_1_3_4_11_2","first-page":"30462","article-title":"Magnetic torque in superoxide ion is the main driving force of dioxygen activation in aerobic life","volume":"38","author":"Minaev B.","year":"2021","unstructured":"B. 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