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From ~151,000 single nuclei, we identified 37 transcriptomically distinct cell types, including multiple types of astrocytes, oligodendrocytes, fibroblasts, and vascular endothelial cells. Our analyses revealed a differential distribution of many cell types among distinct structures. Together with our previous analyses of the anterior segment and retina, the data presented here complete a \u201cVersion 1\u201d cell atlas of the human eye. We used this atlas to map the expression of &gt;180 genes associated with the risk of developing glaucoma, which is known to involve ocular tissues in both anterior and posterior segments as well as the neural retina. Similar methods can be used to investigate numerous additional ocular diseases, many of which are currently untreatable.<\/jats:p>","DOI":"10.1073\/pnas.2306153120","type":"journal-article","created":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T13:40:48Z","timestamp":1691761248000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":59,"title":["Transcriptomic analysis of the ocular posterior segment completes a cell atlas of the human eye"],"prefix":"10.1073","volume":"120","author":[{"given":"Aboozar","family":"Monavarfeshani","sequence":"first","affiliation":[{"name":"Center for Brain Science, Harvard University, Cambridge, MA 02138"},{"name":"F.M. 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