{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T19:40:47Z","timestamp":1793043647183,"version":"4.5.0"},"reference-count":41,"publisher":"National Academy of Sciences","issue":"25","license":[{"start":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:00:00Z","timestamp":1717977600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010573","name":"Stichting Dioraphte","doi-asserted-by":"publisher","award":["16040637"],"award-info":[{"award-number":["16040637"]}],"id":[{"id":"10.13039\/501100010573","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2024,6,18]]},"abstract":"<jats:p>\n                    The WHO recommends mass drug administration (MDA) for intestinal worm infections in areas with over 20% infection prevalence. Recent Cochrane meta-analyses endorse treatment of infected individuals but recommend against MDA. We conducted a theory-agnostic random-effects meta-analysis of the effect of multiple-dose MDA and a cost-effectiveness analysis. We estimate significant effects of MDA on child weight (0.15 kg, 95% CI: 0.07, 0.24;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.001), mid-upper arm circumference (0.20 cm, 95% CI: 0.03, 0.37;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.02), and height (0.09 cm, 95% CI: 0.01, 0.16;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.02) when prevalence is over 20% but not on Hb (0.06 g\/dL, 95% CI: \u22120.01, 0.14;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.1). These results suggest that MDA is a cost-effective intervention, particularly in the settings where it is recommended by the WHO.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2308733121","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T15:00:22Z","timestamp":1718031622000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":6,"title":["Meta-analysis and public policy: Reconciling the evidence on deworming"],"prefix":"10.1073","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4750-9280","authenticated-orcid":false,"given":"Kevin","family":"Croke","sequence":"first","affiliation":[{"name":"Department of Global Health and Population, Harvard T.H. 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