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Nanotube knots can prohibit the tube-to-sheet transformation by blocking water influx into the tubes. Because both nanotubes and DMSs are frequently formed by cellular membranes, understanding the formation and transformation between these membrane morphologies provides insight into the origin and evolution of cellular organelles.<\/jats:p>","DOI":"10.1073\/pnas.2321579121","type":"journal-article","created":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T13:40:46Z","timestamp":1718890846000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":13,"title":["Membrane nanotubes transform into double-membrane sheets at condensate droplets"],"prefix":"10.1073","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8723-7312","authenticated-orcid":false,"given":"Ziliang","family":"Zhao","sequence":"first","affiliation":[{"name":"Max Planck Institute of Colloids and Interfaces, Potsdam 14476, Germany"},{"name":"Leibniz Institute of Photonic Technology e.V., Jena 07745, Germany"},{"name":"Institute of Applied Optics and 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