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Asymptomatic HIV\n                    <jats:sup>+<\/jats:sup>\n                    subjects produced significantly higher levels of MIP-1\u03b1 and MIP-1\u03b2, but not RANTES, than uninfected donors or patients that progressed to AIDS. In contrast, \u03b2 chemokines in plasma were either nondetectable or showed no correlation with clinical status. The high \u03b2-chemokine-mediated anti-HIV activity was against the macrophage tropic isolate HIV-1\n                    <jats:sub>BAL<\/jats:sub>\n                    , with no demonstrable effect on the replication of the T-cell tropic HIV-1\n                    <jats:sub>IIIB<\/jats:sub>\n                    . These findings suggest that constitutive \u03b2-chemokine production may play an important role in the outcome of HIV-1 infection.\n                  <\/jats:p>","DOI":"10.1073\/pnas.240469997","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:44:19Z","timestamp":1027680259000},"page":"13812-13817","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":120,"title":["Higher macrophage inflammatory protein (MIP)-1\u03b1 and MIP-1\u03b2 levels from CD8\n                    <sup>+<\/sup>\n                    T cells are associated with asymptomatic HIV-1 infection"],"prefix":"10.1073","volume":"97","author":[{"given":"Fiorenza","family":"Cocchi","sequence":"first","affiliation":[{"name":"Institute of Human Virology, University of Maryland Biotechnology Institute, University of Maryland, 725 West Lombard Street, Baltimore, MD 21201-1192; and HIV and AIDS Malignancy Branch, National Cancer Institute, 10 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