{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:46:00Z","timestamp":1788482760284,"version":"build-2803163510"},"reference-count":96,"publisher":"National Academy of Sciences","issue":"1","license":[{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI161828"],"award-info":[{"award-number":["R01AI161828"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"HHS | NIH | National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["DE025015"],"award-info":[{"award-number":["DE025015"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"HHS | NIH | National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["T32 GM145388"],"award-info":[{"award-number":["T32 GM145388"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"HHS | NIH | National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["T32 GM136614"],"award-info":[{"award-number":["T32 GM136614"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"HHS | NIH | National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["T90DE030860"],"award-info":[{"award-number":["T90DE030860"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"HHS | NIH | National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["T32 GM145388"],"award-info":[{"award-number":["T32 GM145388"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"HHS | NIH | National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["T32 AI007323"],"award-info":[{"award-number":["T32 AI007323"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2025,1,7]]},"abstract":"<jats:p>\n                    To successfully mount infections, nearly all bacterial pathogens must acquire iron, a key metal cofactor that primarily resides within human hemoglobin.\n                    <jats:italic>Corynebacterium diphtheriae<\/jats:italic>\n                    causes the life-threatening respiratory disease diphtheria and captures hemoglobin for iron scavenging using the surface-displayed receptor HbpA. Here, we show using X-ray crystallography, NMR, and in situ binding measurements that\n                    <jats:italic>C. diphtheriae<\/jats:italic>\n                    selectively captures iron-loaded hemoglobin by partially ensconcing the heme molecules of its \u03b1 subunits. Quantitative growth and heme release measurements are compatible with\n                    <jats:italic>C. diphtheriae<\/jats:italic>\n                    acquiring heme passively released from hemoglobin\u2019s \u03b2 subunits. We propose a model in which HbpA and heme-binding receptors collectively function on the\n                    <jats:italic>C. diphtheriae<\/jats:italic>\n                    surface to capture hemoglobin and its spontaneously released heme. Acquisition mechanisms that exploit the propensity of hemoglobin\u2019s \u03b2 subunit to release heme likely represent a common strategy used by bacterial pathogens to obtain iron during infections.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2411833122","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T13:42:02Z","timestamp":1735652522000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":5,"title":["Molecular basis of hemoglobin binding and heme removal in\n                    <i>Corynebacterium diphtheriae<\/i>"],"prefix":"10.1073","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4323-9276","authenticated-orcid":false,"given":"Brendan J.","family":"Mahoney","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California","place":["Los Angeles"]},{"name":"University of California, Los Angeles-United States Department of Energy Institute of Genomics and Proteomics, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey R.","family":"Lyman","sequence":"additional","affiliation":[{"name":"Laboratory of Respiratory and Special Pathogens, Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration","place":["Silver Spring"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9501-551X","authenticated-orcid":false,"given":"Jordan","family":"Ford","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6159-4354","authenticated-orcid":false,"given":"Jess","family":"Soule","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole A.","family":"Cheung","sequence":"additional","affiliation":[{"name":"University of California, Los Angeles-United States Department of Energy Institute of Genomics and Proteomics, University of California","place":["Los Angeles"]},{"name":"Molecular Biology Institute, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4220-6472","authenticated-orcid":false,"given":"Andrew K.","family":"Goring","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7966-1052","authenticated-orcid":false,"given":"Kat","family":"Ellis-Guardiola","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California","place":["Los Angeles"]},{"name":"University of California, Los Angeles-United States Department of Energy Institute of Genomics and Proteomics, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Collazo","sequence":"additional","affiliation":[{"name":"University of California, Los Angeles-United States Department of Energy Institute of Genomics and Proteomics, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8285-754X","authenticated-orcid":false,"given":"Duilio","family":"Cascio","sequence":"additional","affiliation":[{"name":"University of California, Los Angeles-United States Department of Energy Institute of Genomics and Proteomics, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1611-0469","authenticated-orcid":false,"given":"Hung","family":"Ton-That","sequence":"additional","affiliation":[{"name":"Molecular Biology Institute, University of California","place":["Los Angeles"]},{"name":"Division of Oral and Systemic Health Sciences, School of Dentistry, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Schmitt","sequence":"additional","affiliation":[{"name":"Laboratory of Respiratory and Special Pathogens, Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration","place":["Silver Spring"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5718-3985","authenticated-orcid":false,"given":"Robert T.","family":"Clubb","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California","place":["Los Angeles"]},{"name":"University of California, Los Angeles-United States Department of Energy Institute of Genomics and Proteomics, University of California","place":["Los Angeles"]},{"name":"Molecular Biology Institute, University of California","place":["Los Angeles"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2024,12,31]]},"reference":[{"key":"e_1_3_4_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1898.72440700011001b"},{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-007-7624-1_6"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/br.34.4.378-422.1970"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.185.23.6826-6840.2003"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.2.422-433.2005"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.15.5968"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.59.6.1899-1904.1991"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00602-13"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2013.12.014"},{"key":"e_1_3_4_10_2","first-page":"191","volume-title":"Handbook of Porphyrin Science","author":"Wandersman C.","year":"2012","unstructured":"C. Wandersman, P. Delepelaire, \u201cHeme-delivering proteins in bacteria\u201d in Handbook of Porphyrin Science, G. C. Ferreira, Ed. (World Scientific Publishing Company, 2012), pp. 191\u2013222."},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5MT00170F"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuv009"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2016.03.018"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/9781555819286.ch3"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-060815-014214"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)41877-2"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.28.17385"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-081622-031203"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0000000000000458"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/35051594"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature11369"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-11-451229"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.755934"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.02413-14"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00676-17"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.15698\/mic2022.04.775"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2002-3-9-research0047"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.607679"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.01818.x"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.4.1476-1481.2001"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01784-08"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC07369H"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2023.112368"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.05508-11"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2016.11.027"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00056-07"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.2.837"},{"key":"e_1_3_4_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.179.3.838-845.1997"},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1086\/315534"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00244-13"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00525-10"},{"key":"e_1_3_4_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.06801-11"},{"key":"e_1_3_4_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.05.022"},{"key":"e_1_3_4_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21303"},{"key":"e_1_3_4_45_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1913663117"},{"key":"e_1_3_4_46_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-08991-8"},{"key":"e_1_3_4_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2020.01.031"},{"key":"e_1_3_4_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)41764-9"},{"key":"e_1_3_4_49_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA117.000803"},{"key":"e_1_3_4_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.00349-22"},{"key":"e_1_3_4_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6487"},{"key":"e_1_3_4_52_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00196-21"},{"key":"e_1_3_4_53_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00407-07"},{"key":"e_1_3_4_54_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.03.100149.002103"},{"key":"e_1_3_4_55_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-006-0717-7"},{"key":"e_1_3_4_56_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.14226"},{"key":"e_1_3_4_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2014.01.030"},{"key":"e_1_3_4_58_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-18768-2_13"},{"key":"e_1_3_4_59_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.19.5599-5608.2001"},{"key":"e_1_3_4_60_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.185.8.2528-2537.2003"},{"key":"e_1_3_4_61_2","doi-asserted-by":"publisher","DOI":"10.1002\/pro.3662"},{"key":"e_1_3_4_62_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0104794"},{"key":"e_1_3_4_63_2","doi-asserted-by":"crossref","unstructured":"A. K. Goring The exoproteome and surfaceome of toxigenic corynebacterium diphtheriae 1737 and its response to iron restriction and growth on human hemoglobin. J. Proteome Res. (2024). https:\/\/doi.org\/10.1021\/acs.jproteome.4c00443.","DOI":"10.1021\/acs.jproteome.4c00443"},{"key":"e_1_3_4_64_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01222-23"},{"key":"e_1_3_4_65_2","doi-asserted-by":"publisher","DOI":"10.1107\/S1399004715005817"},{"key":"e_1_3_4_66_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M117.806562"},{"key":"e_1_3_4_67_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2116708119"},{"key":"e_1_3_4_68_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2211939120"},{"key":"e_1_3_4_69_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10172"},{"key":"e_1_3_4_70_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1997.2501619.x"},{"key":"e_1_3_4_71_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.545566"},{"key":"e_1_3_4_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2019.12.023"},{"key":"e_1_3_4_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2022.167623"},{"key":"e_1_3_4_74_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.419119"},{"key":"e_1_3_4_75_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-54970-w"},{"key":"e_1_3_4_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(59)90407-X"},{"key":"e_1_3_4_77_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja062025p"},{"key":"e_1_3_4_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnmrs.2009.05.002"},{"key":"e_1_3_4_79_2","volume-title":"Protein NMR Spectroscopy: Principles and Practice","author":"Cavanagh J.","year":"1996","unstructured":"J. Cavanagh, Protein NMR Spectroscopy: Principles and Practice (Academic Press, 1996)."},{"key":"e_1_3_4_80_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-480-3_22"},{"key":"e_1_3_4_81_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1021614115432"},{"key":"e_1_3_4_82_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(02)00241-3"},{"key":"e_1_3_4_83_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1090-7807(02)00014-9"},{"key":"e_1_3_4_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnmrs.2005.10.001"},{"key":"e_1_3_4_85_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10858-019-00286-w"},{"key":"e_1_3_4_86_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac387"},{"key":"e_1_3_4_87_2","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444909047337"},{"key":"e_1_3_4_88_2","unstructured":"I. J. Tickle STARANISO (Version 3.350 Global Phasing Ltd. Cambridge UK 2023)."},{"key":"e_1_3_4_89_2","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444910007493"},{"key":"e_1_3_4_90_2","unstructured":"G. Bricogne BUSTER (Version 2.10.4 Global Phasing Ltd. Cambridge UK 2023)."},{"key":"e_1_3_4_91_2","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889807021206"},{"key":"e_1_3_4_92_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2006.05.036"},{"key":"e_1_3_4_93_2","doi-asserted-by":"publisher","DOI":"10.1016\/0882-4010(90)90015-I"},{"key":"e_1_3_4_94_2","unstructured":"B. J. Mahoney R. T. Clubb Solution structure of the hemoglobin receptor HbpA from Corynebacterium diphtheria. Biological Magnetic Resonance Data Bank (BMRB). https:\/\/doi.org\/10.13018\/BMR31164. Deposited 9 April 2024."},{"key":"e_1_3_4_95_2","doi-asserted-by":"crossref","unstructured":"B. J. Mahoney R. T. Clubb Solution structure of the hemoglobin receptor HbpA from Corynebacterium diphtheriae. Worldwide Protein Data Bank (wwPDB). https:\/\/doi.org\/10.2210\/pdb9bch\/pdb. Deposited 9 April 2024.","DOI":"10.2210\/pdb9bch\/pdb"},{"key":"e_1_3_4_96_2","doi-asserted-by":"crossref","unstructured":"B. J. Mahoney D. Cascio R. T. Clubb Crystal structure of human hemoglobin in complex with the HbpA receptor from Corynebacterium diphtheriae. Worldwide Protein Data Bank (wwPDB). https:\/\/doi.org\/10.2210\/pdb9bcj\/pdb. Deposited 9 April 2024.","DOI":"10.2210\/pdb9bcj\/pdb"}],"container-title":["Proceedings of the National Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pnas.org\/doi\/pdf\/10.1073\/pnas.2411833122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T13:43:57Z","timestamp":1735652637000},"score":1,"resource":{"primary":{"URL":"https:\/\/pnas.org\/doi\/10.1073\/pnas.2411833122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,31]]},"references-count":96,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,7]]}},"alternative-id":["10.1073\/pnas.2411833122"],"URL":"https:\/\/doi.org\/10.1073\/pnas.2411833122","relation":{},"ISSN":["0027-8424","1091-6490"],"issn-type":[{"value":"0027-8424","type":"print"},{"value":"1091-6490","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,31]]},"assertion":[{"value":"2024-06-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2411833122"}}