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The role of fly HCN in this process can be replaced by human HCN2. Furthermore, unlike the mechanism in olfaction, gustatory ephaptic inhibition is independent of sensillum potential changes, suggesting that the compartmentalized arrangement of neighboring GRNs is dispensable for gustatory ephaptic inhibition. These findings indicate a role for the gating of ephaptic coding to ensure the intake of the essential nutrient despite bitter contaminants present in the feeding niche of\n                    <jats:italic>Drosophila<\/jats:italic>\n                    , and propose that studies in\n                    <jats:italic>Drosophila<\/jats:italic>\n                    gustation could reveal ephaptic principles conserved across diverse animals.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2413134122","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T13:35:51Z","timestamp":1737120951000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":6,"title":["An evolutionarily conserved cation channel tunes the sensitivity of gustatory neurons to ephaptic inhibition in\n                    <i>Drosophila<\/i>"],"prefix":"10.1073","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6101-5053","authenticated-orcid":false,"given":"MinHyuk","family":"Lee","sequence":"first","affiliation":[{"name":"Neurovascular Unit Research Group, Korea Brain Research Institute","place":["Daegu, Republic of Korea"]},{"name":"Department of Anatomy and Cell Biology, Sungkyunkwan University School of Medicine, Samsung Biomedical Research Institute, Samsung Medical Center","place":["Suwon, Republic of Korea"]},{"name":"Department of Biological Sciences, Sungkyunkwan University","place":["Suwon, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9383-7876","authenticated-orcid":false,"given":"Seon Yeong","family":"Kim","sequence":"additional","affiliation":[{"name":"Neurovascular Unit Research Group, Korea Brain Research Institute","place":["Daegu, Republic of Korea"]},{"name":"Department of Brain Sciences, Daegu 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