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Mice deficient in ZDHHC19 or harboring a C142S mutation that disables the palmitoyltransferase activity of ZDHHC19 display phenotypes resembling those of\n                    <jats:italic>Tex38<\/jats:italic>\n                    KO mice. Strikingly, ZDHHC19 palmitoylates ARRDC5, an arrestin family protein regulating sperm differentiation. Overall, our findings indicate that TEX38 forms a stable complex with ZDHHC19 at the plasma membrane of spermatids, which governs downstream S-palmitoylation of proteins essential for morphological transformation of spermatids.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2417943122","type":"journal-article","created":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T15:06:51Z","timestamp":1741014411000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":16,"title":["TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice"],"prefix":"10.1073","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6300-4234","authenticated-orcid":false,"given":"Yuki","family":"Kaneda","sequence":"first","affiliation":[{"name":"Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University","place":["Suita, JAPAN"]},{"name":"Laboratory of Experimental 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