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Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2026,1,27]]},"abstract":"<jats:p>\n                    Understanding the influence of activity on dense amorphous assemblies is crucial for biological processes such as wound healing, embryogenesis, or cancer progression. Here, we study the effect of self-propulsion forces of amplitude\n                    <jats:inline-formula>\n                      <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\" overflow=\"scroll\">\n                        <mml:msub>\n                          <mml:mi>f<\/mml:mi>\n                          <mml:mn>0<\/mml:mn>\n                        <\/mml:msub>\n                      <\/mml:math>\n                    <\/jats:inline-formula>\n                    and persistence time\n                    <jats:inline-formula>\n                      <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\" overflow=\"scroll\">\n                        <mml:msub>\n                          <mml:mi>\u03c4<\/mml:mi>\n                          <mml:mi>p<\/mml:mi>\n                        <\/mml:msub>\n                      <\/mml:math>\n                    <\/jats:inline-formula>\n                    in dense assemblies of soft repulsive particles by simulating a model particle system that interpolates between particulate active matter and biological tissues. We identify the fluid and glass phases of the three-dimensional phase diagram obtained by varying\n                    <jats:inline-formula>\n                      <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\" overflow=\"scroll\">\n                        <mml:msub>\n                          <mml:mi>f<\/mml:mi>\n                          <mml:mn>0<\/mml:mn>\n                        <\/mml:msub>\n                      <\/mml:math>\n                    <\/jats:inline-formula>\n                    ,\n                    <jats:inline-formula>\n                      <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\" overflow=\"scroll\">\n                        <mml:msub>\n                          <mml:mi>\u03c4<\/mml:mi>\n                          <mml:mi>p<\/mml:mi>\n                        <\/mml:msub>\n                      <\/mml:math>\n                    <\/jats:inline-formula>\n                    , and the packing fraction\n                    <jats:inline-formula>\n                      <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\" overflow=\"scroll\">\n                        <mml:mi>\u03d5<\/mml:mi>\n                      <\/mml:math>\n                    <\/jats:inline-formula>\n                    . The morphology of the phase diagram accounts for a nonmonotonic evolution of the relaxation time with\n                    <jats:inline-formula>\n                      <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\" overflow=\"scroll\">\n                        <mml:msub>\n                          <mml:mi>\u03c4<\/mml:mi>\n                          <mml:mi>p<\/mml:mi>\n                        <\/mml:msub>\n                      <\/mml:math>\n                    <\/jats:inline-formula>\n                    , which is a direct consequence of the crossover in the dominant relaxation mechanism, from glassy to jamming. A second major consequence is the evolution of the glassy dynamics from sub-Arrhenius to super-Arrhenius. We show that this tunable glass fragility extends to active systems analogous observations reported for passive particles. This analogy allows us to apply a dynamic scaling analysis proposed for the passive case, in order to account for our results for active systems. Finally, we discuss similarities and differences between our results and recent findings in the context of computational models of biological tissues.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2516624123","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T18:59:25Z","timestamp":1768935565000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":3,"title":["Scaling the glassy dynamics of active particles: Tunable fragility and reentrance"],"prefix":"10.1073","volume":"123","author":[{"given":"Puneet","family":"Pareek","sequence":"first","affiliation":[{"name":"Tata Institute of Fundamental Research","place":["Hyderabad, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0169-7893","authenticated-orcid":false,"given":"Peter","family":"Sollich","sequence":"additional","affiliation":[{"name":"Institute for Theoretical Physics","place":["G\u00f6ttingen, Germany"]},{"name":"University of G\u00f6ttingen","place":["G\u00f6ttingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0977-1947","authenticated-orcid":false,"given":"Saroj Kumar","family":"Nandi","sequence":"additional","affiliation":[{"name":"Tata Institute of Fundamental Research","place":["Hyderabad, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2059-702X","authenticated-orcid":false,"given":"Ludovic","family":"Berthier","sequence":"additional","affiliation":[{"name":"Gulliver, CNRS UMR 7083","place":["Paris, France"]},{"name":"Ecole Sup\u00e9rieure de Physique et Chimie Industrielles de la Ville de Paris","place":["Paris, France"]},{"name":"Universit\u00e9de recherche Paris Sciences et Lettres","place":["Paris, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"e_1_3_4_1_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0705062104"},{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2019.0391"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0479-2"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.187922"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cdev.2021.203727"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmat3025"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2013.0726"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4357"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1075"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2720"},{"key":"e_1_3_4_11_2","first-page":"021025","article-title":"Cell growth rate dictates the onset of glass to fluidlike transition and long time superdiffusion in an evolving cell colony","volume":"8","author":"Malmi-Kakkada A. 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