{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:33:10Z","timestamp":1789453990536,"version":"build-2803163510"},"reference-count":86,"publisher":"National Academy of Sciences","issue":"32","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000286","name":"British Academy","doi-asserted-by":"publisher","award":["pf170053"],"award-info":[{"award-number":["pf170053"]}],"id":[{"id":"10.13039\/501100000286","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006363","name":"National Geographic Society","doi-asserted-by":"publisher","award":["HJ-8641-09"],"award-info":[{"award-number":["HJ-8641-09"]}],"id":[{"id":"10.13039\/100006363","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006363","name":"National Geographic Society","doi-asserted-by":"publisher","award":["HJ-043R-17"],"award-info":[{"award-number":["HJ-043R-17"]}],"id":[{"id":"10.13039\/100006363","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["MA 5298\/3"],"award-info":[{"award-number":["MA 5298\/3"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2026,8,11]]},"abstract":"<jats:p>\n                    The domestication of plants in southwest Asia was an evolutionary process that took place over several millennia in the Early Holocene. During this time, domestic species developed distinct traits that distinguished them from their wild counterparts. Current models of plant domestication emphasize the role of genetic selection in the evolution of these traits, viewing these as heritable adaptations that arose in response to selective pressures associated with human cultivation. In cereals, domestication resulted in the evolution of nonshattering rachis and increased grain size, two traits that can be tracked directly in the archaeobotanical record. Analyses of Early Neolithic cereal remains demonstrate that grain size increase occurred prior to the evolution of nonshattering rachis, a sequence that is often interpreted as evidence of selection for larger grains under cultivation, specifically tillage. Here, we combine morphological and metrical analyses of cereal remains, stable carbon isotope analysis, and weed ecology to test this hypothesis, using three assemblages from the southern Levant: Pre-Pottery Neolithic A Sharara (\n                    <jats:italic toggle=\"yes\">c.<\/jats:italic>\n                    9250\u20139200 cal BCE), Pre-Pottery Neolithic A el-Hemmeh (\n                    <jats:italic toggle=\"yes\">c.<\/jats:italic>\n                    9400\u20138700 cal BCE), and Late Pre-Pottery Neolithic B el-Hemmeh (\n                    <jats:italic toggle=\"yes\">c.<\/jats:italic>\n                    7500\u20137000 cal BCE). Our findings indicate that increased grain size in the Early Holocene can be better understood as a plastic response to variation in growing conditions, specifically moisture, rather than as a result of genetic selection for increased grain size under cultivation. We propose that cereal evolution in southwest Asia was initially driven by developmental plasticity, followed by genetic selection.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2535274123","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T17:59:11Z","timestamp":1785866351000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":1,"title":["Developmental plasticity under human management shaped cereal evolution prior to domestication in the Early Holocene southern Levant"],"prefix":"10.1073","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9769-4704","authenticated-orcid":false,"given":"Jade","family":"Whitlam","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052gg0110","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Archaeology, University of Oxford","place":["Oxford, United Kingdom"]},{"id":[{"id":"https:\/\/ror.org\/052gg0110","id-type":"ROR","asserted-by":"publisher"}],"name":"Department for Continuing Education, University of Oxford","place":["Oxford, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3203-913X","authenticated-orcid":false,"given":"Pascal","family":"Flohr","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052gg0110","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Archaeology, University of Oxford","place":["Oxford, United Kingdom"]},{"name":"Institute for Prehistoric and Protohistoric Archaeology, University of Kiel","place":["Kiel, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6716-8890","authenticated-orcid":false,"given":"Amy","family":"Bogaard","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052gg0110","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Archaeology, University of Oxford","place":["Oxford, United Kingdom"]},{"name":"Sante Fe Institute","place":["Sante Fe"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9630-7589","authenticated-orcid":false,"given":"Michael","family":"Charles","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052gg0110","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Archaeology, University of Oxford","place":["Oxford, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0330-8006","authenticated-orcid":false,"given":"Bill","family":"Finlayson","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052gg0110","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Archaeology, University of Oxford","place":["Oxford, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1649-336X","authenticated-orcid":false,"given":"Cheryl A.","family":"Makarewicz","sequence":"additional","affiliation":[{"name":"Institute for Prehistoric and Protohistoric Archaeology, University of Kiel","place":["Kiel, Germany"]},{"name":"Archaeology Stable Isotope Laboratory, University of Kiel","place":["Kiel, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2026,8,4]]},"reference":[{"key":"e_1_3_4_1_2","first-page":"11","article-title":"Das domestikationssyndrom","volume":"32","author":"Hammer K.","year":"1984","unstructured":"K. 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(ICARDA, 1998), pp. 121\u2013131."},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/00758914.2018.1424746"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.3406\/paleo.2004.1010"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1191\/095968301678302823"},{"key":"e_1_3_4_9_2","first-page":"209","volume-title":"An Early Neolithic Village in the Jordan Valley","author":"Kislev M. E.","year":"1997","unstructured":"M. E. Kislev, \u201cEarly agriculture and paleoecology of Netiv Hagdud\u201d in An Early Neolithic Village in the Jordan Valley, O. Bar-Yosef, A. Gopher, Eds. (Peabody Museum of Archaeology and Ethnology, Harvard University, 1997), pp. 209\u2013236."},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1236743"},{"key":"e_1_3_4_11_2","first-page":"65","article-title":"The Plant husbandry of Aceramic \u00c7ayon\u00fc, S.E. 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