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CD4 T cells, highly activated by organoid infection, limited EBV\n                    <jats:sup>+<\/jats:sup>\n                    B cell outgrowth in both primary and secondary EBV infection. Our findings demonstrate human tonsil organoids as a physiologically relevant model to investigate key aspects of EBV immunity and pathogenesis.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2603586123","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:33:32Z","timestamp":1786646012000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":1,"title":["A tonsil organoid model reveals Epstein\u2013Barr virus\u2013infected germinal center B cell states during primary infection"],"prefix":"10.1073","volume":"123","author":[{"given":"Mahina Tabassum","family":"Mitul","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04gyf1771","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Physiology and Biophysics, Institute for Immunology, and Center for Virus Research, University of California 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