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The resulting structure exhibits weak and nondirectional interhelical interactions within the (\n                    <jats:italic toggle=\"yes\">bc<\/jats:italic>\n                    ) plane and comparatively strong and directional intrahelical hydrogen bonding along the\n                    <jats:italic toggle=\"yes\">a<\/jats:italic>\n                    axis. This structural anisotropy gives rise to single crystals with large aspect ratios and distinct mechanical behavior. This realization of two rare structural motifs within a single crystal shows the capability of simple organic molecules to form complex structures and highlights an untapped potential for symmetry engineering in molecular solids through the interplay of intermolecular interactions with pronounced differences in strength and directionality.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2608878123","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:36:36Z","timestamp":1791999396000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":0,"title":["Ice-ray pentagonal packing of pseudo-fivefold 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