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It has been asserted that this new outbreak finds its origin in a single introduction event into the island, offering an opportunity to exploit viral genomic data to understand the epidemiological and dispersal dynamics of the introduced transmission chain. We sequenced &gt;3,000 viral genomes collected during the epidemic. Harnessing this genomic dataset, we used several phylogeographic and phylodynamic approaches to unravel the paths taken by the transmission chain and the external factors that might have impacted its dispersal and epidemiological dynamics on the island. Our analyses highlight a dispersal pattern in line with a gravity-model dynamic with viral transition events being more frequent from and toward more populated areas. Our analyses reveal that the transmission chain was overall spatially intermixed, with frequent exchanges among residential areas. In addition, we show that the temporal dynamic and intensity of the epidemic were associated with climatic variables, namely temperature and precipitation. Our results also show that in theory, the population immunity\u2014resulting from this epidemic and the previous one (2005\u20132006)\u2014could be sufficient to explain on its own the decrease in the transmission rate that led to the end of the epidemic. While a short-term resurgence cannot be excluded, the risk of a large-scale circulation of the virus in the human population appears therefore relatively limited in the upcoming seasons.<\/jats:p>","DOI":"10.1073\/pnas.2621019123","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:37:27Z","timestamp":1789580247000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":0,"title":["Unraveling the epidemiological and dispersal dynamics of the 2024\u20132025 chikungunya virus epidemic on R\u00e9union Island"],"prefix":"10.1073","volume":"123","author":[{"given":"Etienne","family":"Frumence","sequence":"first","affiliation":[{"name":"Laboratoire de Virologie, Centre Hospitalier Universitaire F\u00e9lix Guyon","place":["Saint-Denis, France"]},{"name":"Centre National de R\u00e9f\u00e9rence Associ\u00e9 des Arbovirus","place":["Saint-Denis, 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