{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T14:33:10Z","timestamp":1781101990465,"version":"3.54.1"},"reference-count":0,"publisher":"National Academy of Sciences","issue":"1","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[1969,9]]},"abstract":"<jats:p>Skin cells from albino mouse embryos have been shown to synthesize melanin after exposure to a nucleoprotein fraction of cells from pigmented mice. Although transformed clones were not found in any of 37 control experiments, at least 15 transformations took place in 10 of a series of 49 experiments using undegraded DNA. The active component in the transforming material appears to be DNA because DNase-treated preparations did not induce melanin synthesis.<\/jats:p>","DOI":"10.1073\/pnas.64.1.184","type":"journal-article","created":{"date-parts":[[2006,5,31]],"date-time":"2006-05-31T02:15:09Z","timestamp":1149041709000},"page":"184-189","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":17,"title":["INDUCTION OF MELANIN SYNTHESIS IN ALBINO MOUSE SKIN BY DNA FROM PIGMENTED MICE"],"prefix":"10.1073","volume":"64","author":[{"given":"Elena","family":"Ottolenghi-Nightingale","sequence":"first","affiliation":[{"name":"DEPARTMENT OF MICROBIOLOGY, CORNELL UNIVERSITY MEDICAL COLLEGE, NEW YORK, NEW YORK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[1969,9]]},"container-title":["Proceedings of the National Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pnas.org\/doi\/pdf\/10.1073\/pnas.64.1.184","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T10:18:35Z","timestamp":1649845115000},"score":1,"resource":{"primary":{"URL":"https:\/\/pnas.org\/doi\/full\/10.1073\/pnas.64.1.184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,9]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1969,9]]}},"alternative-id":["10.1073\/pnas.64.1.184"],"URL":"https:\/\/doi.org\/10.1073\/pnas.64.1.184","relation":{},"ISSN":["0027-8424","1091-6490"],"issn-type":[{"value":"0027-8424","type":"print"},{"value":"1091-6490","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,9]]},"assertion":[{"value":"1969-09-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}