{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T16:43:05Z","timestamp":1781109785483,"version":"3.54.1"},"reference-count":0,"publisher":"National Academy of Sciences","issue":"8","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[1972,8]]},"abstract":"<jats:p>\n                    Studies of variously liganded hemoglobins (both from human and rabbit) by natural-abundance\n                    <jats:sup>13<\/jats:sup>\n                    C NMR spectroscopy have revealed apparent conformational differences that have been interpreted on the basis of two quaternary structures for the \u03b1\n                    <jats:sub>2<\/jats:sub>\n                    \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    tetramer, and variable tertiary structures for the individual \u03b1 and \u03b2 subunits. In solution, rabbit hemoglobins appear to have somewhat more flexibility than human hemoglobins.\n                  <\/jats:p>","DOI":"10.1073\/pnas.69.8.2193","type":"journal-article","created":{"date-parts":[[2006,5,31]],"date-time":"2006-05-31T02:37:04Z","timestamp":1149043024000},"page":"2193-2197","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":16,"title":["Conformational Studies of Various Hemoglobins by Natural-Abundance\n                    <sup>13<\/sup>\n                    C NMR Spectroscopy"],"prefix":"10.1073","volume":"69","author":[{"given":"R. B.","family":"Moon","sequence":"first","affiliation":[{"name":"Gates and Crellin Laboratories of Chemistry, California Institute of Technology, Pasadena, Calif. 91109"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. H.","family":"Richards","sequence":"additional","affiliation":[{"name":"Gates and Crellin Laboratories of Chemistry, California Institute of Technology, Pasadena, Calif. 91109"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[1972,8]]},"container-title":["Proceedings of the National Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pnas.org\/doi\/pdf\/10.1073\/pnas.69.8.2193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T10:42:05Z","timestamp":1649846525000},"score":1,"resource":{"primary":{"URL":"https:\/\/pnas.org\/doi\/full\/10.1073\/pnas.69.8.2193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,8]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1972,8]]}},"alternative-id":["10.1073\/pnas.69.8.2193"],"URL":"https:\/\/doi.org\/10.1073\/pnas.69.8.2193","relation":{},"ISSN":["0027-8424","1091-6490"],"issn-type":[{"value":"0027-8424","type":"print"},{"value":"1091-6490","type":"electronic"}],"subject":[],"published":{"date-parts":[[1972,8]]},"assertion":[{"value":"1972-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}