{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T19:35:57Z","timestamp":1790796957467,"version":"4.1.0"},"reference-count":0,"publisher":"National Academy of Sciences","issue":"8","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[1992,4,15]]},"abstract":"<jats:p>This experiment examined the effects of diazepam (DZP) on acquisition and retention of an inhibitory avoidance response by rats with excitotoxic-induced lesions of central (CE), lateral (LAT), or basolateral (BL) amygdala nuclei. Sham-operated and lesioned rats received i.p. injections of DZP (2.0 mg per kg of body weight) 30 min before training in a continuous multiple-trial inhibitory avoidance task. Retention was tested 48 h later. Acquisition was not impaired by the lesions or the DZP. Retention was impaired in animals with CE and LAT lesions in comparison with sham-operated controls. DZP impaired retention in the sham-operated controls as well as CE- and LAT-lesioned animals but did not affect retention in animals with BL lesions. These findings indicate that the DZP-induced anterograde amnesia for inhibitory avoidance training is mediated through influences involving the BL amygdala nucleus.<\/jats:p>","DOI":"10.1073\/pnas.89.8.3615","type":"journal-article","created":{"date-parts":[[2006,5,31]],"date-time":"2006-05-31T08:19:52Z","timestamp":1149063592000},"page":"3615-3619","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":78,"title":["Basolateral amygdala lesions block diazepam-induced anterograde amnesia in an inhibitory avoidance task."],"prefix":"10.1073","volume":"89","author":[{"given":"C","family":"Tomaz","sequence":"first","affiliation":[{"name":"Laboratory of Psychobiology, University of Sao Paulo, Ribeirao Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Dickinson-Anson","sequence":"additional","affiliation":[{"name":"Laboratory of Psychobiology, University of Sao Paulo, Ribeirao Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J L","family":"McGaugh","sequence":"additional","affiliation":[{"name":"Laboratory of Psychobiology, University of Sao Paulo, Ribeirao Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[1992,4,15]]},"container-title":["Proceedings of the National Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pnas.org\/doi\/pdf\/10.1073\/pnas.89.8.3615","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T13:43:13Z","timestamp":1649857393000},"score":1,"resource":{"primary":{"URL":"https:\/\/pnas.org\/doi\/full\/10.1073\/pnas.89.8.3615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,4,15]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1992,4,15]]}},"alternative-id":["10.1073\/pnas.89.8.3615"],"URL":"https:\/\/doi.org\/10.1073\/pnas.89.8.3615","relation":{},"ISSN":["0027-8424","1091-6490"],"issn-type":[{"value":"0027-8424","type":"print"},{"value":"1091-6490","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,4,15]]},"assertion":[{"value":"1992-04-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}