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Expression of WIP in human B cells, but not of a WIP truncation mutant that lacks the actin binding motif, increased polymerized actin content and induced the appearance of actin-containing cerebriform projections on the cell surface. These results suggest that WIP plays a role in cortical actin assembly that may be important for lymphocyte function.<\/jats:p>","DOI":"10.1073\/pnas.94.26.14671","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:31:39Z","timestamp":1027679499000},"page":"14671-14676","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":310,"title":["WIP, a protein associated with Wiskott\u2013Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid\u2009cells"],"prefix":"10.1073","volume":"94","author":[{"given":"Narayanaswamy","family":"Ramesh","sequence":"first","affiliation":[{"name":"Division of Immunology, Children\u2019s Hospital and Division of Experimental Medicine, Brigham and Women\u2019s Hospital, and Departments of Pediatrics and Medicine, Harvard Medical School, Boston, MA 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00e9s 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