{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:51:15Z","timestamp":1791183075717,"version":"4.1.0"},"reference-count":36,"publisher":"National Academy of Sciences","issue":"7","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[1997,4]]},"abstract":"<jats:p>\n                    The gene\n                    <jats:italic>unc-76<\/jats:italic>\n                    (\n                    <jats:italic>unc<\/jats:italic>\n                    , uncoordinated) is necessary for normal axonal bundling and elongation within axon bundles in the nematode\n                    <jats:italic>Caenorhabditis elegans<\/jats:italic>\n                    . The UNC-76 protein and two human homologs identified as expressed sequence tags are not similar to previously characterized proteins and thus represent a new protein family. At least one of these human homologs can function in\n                    <jats:italic>C. elegans<\/jats:italic>\n                    , suggesting that it, like UNC-76, acts in axonal outgrowth. We propose that the UNC-76 protein, which is found in cell bodies and processes of all neurons throughout development, either has a structural role in the formation and maintenance of axonal bundles or transduces signals to the intracellular machinery that regulates axonal extension and adhesion.\n                  <\/jats:p>","DOI":"10.1073\/pnas.94.7.3414","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:31:39Z","timestamp":1027679499000},"page":"3414-3419","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":158,"title":["The\n                    <i>Caenorhabditis elegans<\/i>\n                    gene\n                    <i>unc-76<\/i>\n                    and its human homologs define a new gene family involved in axonal outgrowth and\u2009fasciculation"],"prefix":"10.1073","volume":"94","author":[{"given":"Laird","family":"Bloom","sequence":"first","affiliation":[{"name":"Howard Hughes Medical Institute, Department of Biology, Room 68-425, Massachusetts Institute of Technology, 77 Massachusetts Avenue,  Cambridge, MA 02139"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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