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Plants mutated at the\n                    <jats:italic>DND1<\/jats:italic>\n                    locus are defective in HR cell death but retain characteristic responses to avirulent\n                    <jats:italic>Pseudomonas syringae<\/jats:italic>\n                    such as induction of pathogenesis-related gene expression and strong restriction of pathogen growth. Mutant\n                    <jats:italic>dnd1<\/jats:italic>\n                    plants also exhibit enhanced resistance against a broad spectrum of virulent fungal, bacterial, and viral pathogens. The resistance against virulent pathogens in\n                    <jats:italic>dnd1<\/jats:italic>\n                    plants is quantitatively less strong and is differentiable from the gene-for-gene resistance mediated by resistance genes\n                    <jats:italic>RPS2<\/jats:italic>\n                    and\n                    <jats:italic>RPM1<\/jats:italic>\n                    . Levels of salicylic acid compounds and mRNAs for pathogenesis-related genes are elevated constitutively in\n                    <jats:italic>dnd1<\/jats:italic>\n                    plants. This constitutive induction of systemic acquired resistance may substitute for HR cell death in potentiating the stronger gene-for-gene defense response. Although cell death may contribute to defense signal transduction in wild-type plants, the\n                    <jats:italic>dnd1<\/jats:italic>\n                    mutant demonstrates that strong restriction of pathogen growth can occur in the absence of extensive HR cell death in the gene-for-gene resistance response of\n                    <jats:italic>Arabidopsis<\/jats:italic>\n                    against\n                    <jats:italic>P. syringae<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1073\/pnas.95.13.7819","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:40:52Z","timestamp":1027680052000},"page":"7819-7824","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":368,"title":["Gene-for-gene disease resistance without the hypersensitive response in\n                    <i>Arabidopsis dnd1<\/i>\n                    mutant"],"prefix":"10.1073","volume":"95","author":[{"given":"I-ching","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801; and Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom NR4 7UH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Parker","sequence":"additional","affiliation":[{"name":"Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801; and Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom NR4 7UH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew F.","family":"Bent","sequence":"additional","affiliation":[{"name":"Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801; and Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom NR4 7UH"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[1998,6,23]]},"reference":[{"key":"e_1_3_2_1_2","volume-title":"Wheat Rusts: An Atlas of Resistance Genes","author":"McIntosh R A","year":"1995","unstructured":"R A McIntosh, C R Wellings, R F Park Wheat Rusts: An Atlas of Resistance Genes (Commonwealth Scientific and Industrial Research Organization, Australia, and Kluwer, Dordrecht, The Netherlands, 1995)."},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.2307\/3870227"},{"key":"e_1_3_2_3_2","volume-title":"Plant Pathology","author":"Agrios G N","year":"1997","unstructured":"G N Agrios Plant Pathology (Academic, San Diego, 1997)."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.2307\/3870228"},{"key":"e_1_3_2_5_2","first-page":"653","volume":"32","author":"Flor H H","year":"1942","unstructured":"H H Flor Phytopathology 32, 653\u2013669 (1942).","journal-title":"Phytopathology"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.2307\/3870222"},{"key":"e_1_3_2_7_2","first-page":"1773","volume":"8","author":"Hammond-Kosack K E","year":"1996","unstructured":"K E Hammond-Kosack, J D G Jones Plant Cell 8, 1773\u20131791 (1996).","journal-title":"Plant Cell"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.2307\/3870230"},{"key":"e_1_3_2_9_2","first-page":"193","volume":"4","author":"Stakman E C","year":"1915","unstructured":"E C Stakman J Agric Res 4, 193\u2013199 (1915).","journal-title":"J Agric Res"},{"key":"e_1_3_2_10_2","volume-title":"The Hypersensitive Reaction in Plants to Pathogens: A Resistance Phenomenon","author":"Goodman R N","year":"1994","unstructured":"R N Goodman, A J Novacky The Hypersensitive Reaction in Plants to Pathogens: A Resistance Phenomenon (Am. 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