{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:20:02Z","timestamp":1790504402265,"version":"4.1.0"},"reference-count":30,"publisher":"National Academy of Sciences","issue":"26","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[1998,12,22]]},"abstract":"<jats:p>\n                    <jats:italic>teashirt<\/jats:italic>\n                    was initially identified as a gene required for the specification of the trunk segments in\n                    <jats:italic>Drosophila<\/jats:italic>\n                    embryogenesis and encodes a transcription factor with zinc finger motifs. We report here that targeted expression of\n                    <jats:italic>teashirt<\/jats:italic>\n                    in imaginal discs is sufficient to induce ectopic eye formation in non-eye tissues, a phenotype similar to that produced from targeted expression of\n                    <jats:italic>eyeless<\/jats:italic>\n                    ,\n                    <jats:italic>dachshund<\/jats:italic>\n                    , and\n                    <jats:italic>eyes absent<\/jats:italic>\n                    . Furthermore,\n                    <jats:italic>teashirt<\/jats:italic>\n                    and\n                    <jats:italic>eyeless<\/jats:italic>\n                    induce the expression of each other, suggesting that\n                    <jats:italic>teashirt<\/jats:italic>\n                    is part of the gene network that functions to specify eye identity.\n                  <\/jats:p>","DOI":"10.1073\/pnas.95.26.15508","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:40:11Z","timestamp":1027680011000},"page":"15508-15512","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":86,"title":["Targeted expression of\n                    <i>teashirt<\/i>\n                    induces ectopic eyes in\n                    <i>Drosophila<\/i>"],"prefix":"10.1073","volume":"95","author":[{"given":"Duojia","family":"Pan","sequence":"first","affiliation":[{"name":"Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720-3200"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald M.","family":"Rubin","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720-3200"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[1998,12,22]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/355750a0"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0894-463"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90284-6"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7914031"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7892602"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.120.12.3473"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90115-7"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(94)90308-5"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.124.23.4819"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80481-X"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80480-8"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.124.1.45"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.125.12.2181"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90209-H"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.120.8.2287"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004270050101"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80335-9"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00636536"},{"key":"e_1_3_3_19_2","volume-title":"Drosophila: A Laboratory Manual","author":"Ashburner M","year":"1989","unstructured":"M Ashburner Drosophila: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY, 1989)."},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.10.5195"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.22.12418"},{"key":"e_1_3_3_22_2","first-page":"585","volume":"5","author":"Staehling-Hampton K","year":"1994","unstructured":"K Staehling-Hampton, P D Jackson, M J Clark, A H Brand, F M Hoffmann Cell Growth Differ 5, 585\u2013593 (1994).","journal-title":"Cell Growth Differ"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/neu.480220503"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.5.4.583"},{"key":"e_1_3_3_25_2","first-page":"747","volume-title":"The Development of Drosophila melanogaster","author":"Cohen S M","year":"1993","unstructured":"S M Cohen The Development of Drosophila melanogaster (Cold Spring Harbor Lab. Press, Plainview, NY), pp. 747\u2013841 (1993)."},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.117.4.1223"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.120.10.2799"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.121.9.2799"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.115.4.1017"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80126-9"}],"container-title":["Proceedings of the National Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pnas.org\/doi\/pdf\/10.1073\/pnas.95.26.15508","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T16:04:48Z","timestamp":1649865888000},"score":1,"resource":{"primary":{"URL":"https:\/\/pnas.org\/doi\/full\/10.1073\/pnas.95.26.15508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,12,22]]},"references-count":30,"journal-issue":{"issue":"26","published-print":{"date-parts":[[1998,12,22]]}},"alternative-id":["10.1073\/pnas.95.26.15508"],"URL":"https:\/\/doi.org\/10.1073\/pnas.95.26.15508","relation":{},"ISSN":["0027-8424","1091-6490"],"issn-type":[{"value":"0027-8424","type":"print"},{"value":"1091-6490","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,12,22]]},"assertion":[{"value":"1998-10-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1998-12-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}