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Three hypotheses are considered: (\n                    <jats:italic>i<\/jats:italic>\n                    ) The\n parahippocampal cortex is critically involved in the acquisition of\n exocentric spatial information in humans; (\n                    <jats:italic>ii<\/jats:italic>\n                    )\n separable, posterior, dorsal, and ventral cortical regions subserve the\n perception and long term representation of position and identity,\n respectively, of landmarks; and (\n                    <jats:italic>iii<\/jats:italic>\n                    ) there is a\n distinct area of the ventral occipitotemporal cortex that responds\n maximally to building stimuli and may play a role in the perception of\n salient landmarks. We conclude with a discussion of the inferential\n limitations of neuroimaging and lesion studies. It is proposed that\n combining these two approaches allows for inferences regarding the\n computational involvement of a neuroanatomical substrate in a given\n cognitive process although neither method can strictly support this\n conclusion alone.\n                  <\/jats:p>","DOI":"10.1073\/pnas.95.3.839","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:40:11Z","timestamp":1027680011000},"page":"839-846","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":123,"title":["Neural components of topographical\u2009representation"],"prefix":"10.1073","volume":"95","author":[{"given":"Geoffrey K.","family":"Aguirre","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Pennsylvania Medical Center,\r Philadelphia, PA 19104-4283"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Zarahn","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Pennsylvania Medical Center,\r Philadelphia, PA 19104-4283"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"D\u2019Esposito","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Pennsylvania Medical Center,\r Philadelphia, PA 19104-4283"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[1998,2,3]]},"reference":[{"key":"e_1_3_3_1_2","volume-title":"The Hippocampus as a Cognitive Map","author":"O\u2019Keefe J","year":"1978","unstructured":"J O\u2019Keefe, L Nadel The Hippocampus as a Cognitive Map (Oxford Univ. 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