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However, interactions between US2 or US11 and the heavy chain are maintained in the absence of the class I cytosolic domain, as shown by chemical crosslinking\n                    <jats:italic>in vivo<\/jats:italic>\n                    and coprecipitation when translated\n                    <jats:italic>in vitro<\/jats:italic>\n                    . Thus, substrate recognition and accelerated destruction of the heavy chain, as facilitated by US2 or US11, are separable events.\n                  <\/jats:p>","DOI":"10.1073\/pnas.96.15.8516","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:40:52Z","timestamp":1027680052000},"page":"8516-8521","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":71,"title":["The cytosolic tail of class I MHC heavy chain is required for its dislocation by the human cytomegalovirus US2 and US11 gene products"],"prefix":"10.1073","volume":"96","author":[{"given":"Craig M.","family":"Story","sequence":"first","affiliation":[{"name":"Department of Pathology, Harvard Medical School, Boston, MA 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margo H.","family":"Furman","sequence":"additional","affiliation":[{"name":"Department of Pathology, Harvard Medical School, Boston, MA 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