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The prerequisite for developing any system of early warning is a detailed understanding of the factors involved in epidemic genesis. In this report we discuss the potential causes of the interepidemic periods in dengue hemorrhagic fever in Bangkok and of\n                    <jats:italic>Plasmodium falciparum<\/jats:italic>\n                    malaria in a highland area of western Kenya. The alternative causes are distinguished by a retrospective analysis of two unique and contemporaneous 33-year time series of epidemiological and associated meteorological data recorded at these two sites. We conclude that intrinsic population dynamics offer the most parsimonious explanation for the observed interepidemic periods of disease in these locations.\n                  <\/jats:p>","DOI":"10.1073\/pnas.97.16.9335","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:41:48Z","timestamp":1027680108000},"page":"9335-9339","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":152,"title":["Etiology of interepidemic periods of mosquito-borne disease"],"prefix":"10.1073","volume":"97","author":[{"given":"Simon I.","family":"Hay","sequence":"first","affiliation":[{"name":"Trypanosomiasis and Land Use in Africa Research Group, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; National Aeronautics and Space Administration, Goddard Space Flight Center, Code 902, Building 32\/S130E, Greenbelt, MD 20771; Department of International Health, School of Hygiene and Public Health, Johns Hopkins University, Hampton House, 624 North Broadway, Baltimore, MD 21205; Department of Virus Diseases, Walter Reed Army Institute of Research, 503..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica F.","family":"Myers","sequence":"additional","affiliation":[{"name":"Trypanosomiasis and Land Use in Africa Research Group, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; National Aeronautics and Space Administration, Goddard Space Flight Center, Code 902, Building 32\/S130E, Greenbelt, MD 20771; Department of International Health, School of Hygiene and Public Health, Johns Hopkins University, Hampton House, 624 North Broadway, Baltimore, MD 21205; Department of Virus Diseases, Walter Reed Army Institute of Research, 503..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald S.","family":"Burke","sequence":"additional","affiliation":[{"name":"Trypanosomiasis and Land Use in Africa Research Group, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; National Aeronautics and Space Administration, Goddard Space Flight Center, Code 902, Building 32\/S130E, Greenbelt, MD 20771; Department of International Health, School of Hygiene and Public Health, Johns Hopkins University, Hampton House, 624 North Broadway, Baltimore, MD 21205; Department of Virus Diseases, Walter Reed Army Institute of Research, 503..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Vaughn","sequence":"additional","affiliation":[{"name":"Trypanosomiasis and Land Use in Africa Research Group, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; National Aeronautics and Space Administration, Goddard Space Flight Center, Code 902, Building 32\/S130E, Greenbelt, MD 20771; Department of International Health, School of Hygiene and Public Health, Johns Hopkins University, Hampton House, 624 North Broadway, Baltimore, MD 21205; Department of Virus Diseases, Walter Reed Army Institute of Research, 503..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Endy","sequence":"additional","affiliation":[{"name":"Trypanosomiasis and Land Use in Africa Research Group, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; National Aeronautics and Space Administration, Goddard Space Flight Center, Code 902, Building 32\/S130E, Greenbelt, MD 20771; Department of International Health, School of Hygiene and Public Health, Johns Hopkins University, Hampton House, 624 North Broadway, Baltimore, MD 21205; Department of Virus Diseases, Walter Reed Army Institute of Research, 503..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisalak","family":"Ananda","sequence":"additional","affiliation":[{"name":"Trypanosomiasis and Land Use in Africa Research Group, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; National Aeronautics and Space Administration, Goddard Space Flight Center, Code 902, Building 32\/S130E, Greenbelt, MD 20771; Department of International Health, School of Hygiene and Public Health, Johns Hopkins University, Hampton House, 624 North Broadway, Baltimore, MD 21205; Department of Virus Diseases, Walter Reed Army Institute of Research, 503..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. 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