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Divergent subfamilies have been found in two families.\n Past mobility was demonstrated by evidence of MITE insertions that\n resulted in the duplication of specific TA, TAA, or 8-bp targets. Some\n of these MITEs share the same target duplications and similar terminal\n sequences with MITEs and other DNA transposons in human and other\n organisms. MITEs in\n                    <jats:italic>A. gambiae<\/jats:italic>\n                    range from 40 to 1340\n copies per genome, much less abundant than MITEs in the yellow fever\n mosquito,\n                    <jats:italic>Aedes aegypti<\/jats:italic>\n                    . Statistical analyses suggest\n that most\n                    <jats:italic>A. gambiae<\/jats:italic>\n                    MITEs are in highly AT-rich\n regions, many of which are closely associated with each other. The\n analyses of these novel MITEs underscored interesting questions\n regarding their diversity, origin, evolution, and relationships to the\n host genomes. The discovery of diverse families of MITEs in\n                    <jats:italic>A.\n gambiae<\/jats:italic>\n                    has important practical implications in light of\n current efforts to control malaria by replacing vector mosquitoes with\n genetically modified refractory mosquitoes. Finally, the systematic\n approach to rapidly identify novel MITEs should have broad applications\n for the analysis of the ever-growing sequence databases of a wide range\n of organisms.\n                  <\/jats:p>","DOI":"10.1073\/pnas.98.4.1699","type":"journal-article","created":{"date-parts":[[2012,7,26]],"date-time":"2012-07-26T19:12:10Z","timestamp":1343329930000},"page":"1699-1704","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":107,"title":["Eight novel families of miniature inverted repeat transposable elements in the African malaria mosquito,\n                    <i>Anopheles gambiae<\/i>"],"prefix":"10.1073","volume":"98","author":[{"given":"Zhijian","family":"Tu","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Virginia Polytechnic Institute and\r State University, Blacksburg, VA 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