{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T15:13:59Z","timestamp":1770995639065,"version":"3.50.1"},"reference-count":41,"publisher":"Proceedings of the National Academy of Sciences","issue":"6","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[1998,3,17]]},"abstract":"<jats:p>\n            Somatosensory stimuli are known to activate the postcentral gyrus,\n and neurons there fire when the skin is in contact with objects. Also\n neurons in the lateral fissure, the parietal operculum, fire when rough\n surfaces are felt. However the localization of somatosensory\n association areas in humans is largely unknown and differences in\n functional contributions between somatosensory association areas has\n not been previously demonstrated. For these reasons the regional\n cerebral blood flow was measured with\n            <jats:sup>15<\/jats:sup>\n            O-butanol and\n positron-emission tomography in two groups of young volunteers\n discriminating the lengths, shapes, and roughness of objects with their\n right hand. Roughness discrimination activated the lateral parietal\n opercular cortex significantly more than did length or shape\n discrimination. A Boolean intersection of the cluster images showing\n the statistical significant increases of length and shape\n discrimination demonstrated that shape and length discrimination\n activated the same cortical field lining the anterior part of the\n intraparietal sulcus (IPA). Shape and length discrimination activated\n IPA significantly more than did roughness discriminaton. These findings\n demonstrate a separation in functional contributions of lateral\n parietal opercular cortex and IPA. The results indicate different\n cortical processing streams for the somatosensory submodalities\n microgeometry and macrogeometry.\n          <\/jats:p>","DOI":"10.1073\/pnas.95.6.3295","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:40:11Z","timestamp":1027694411000},"page":"3295-3300","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":143,"title":["Shape and roughness activate different somatosensory areas in the human\u2009brain"],"prefix":"10.1073","volume":"95","author":[{"given":"Per E.","family":"Roland","sequence":"first","affiliation":[{"name":"Division of Human Brain Research, Department of Neuroscience, The\r Karolinska Institute, S-171 77 Stockholm, Sweden; Department\r of Psychiatry, Royal Prince Alfred Hospital, Camperdown NSW 2050,\r Sydney, Australia; and Institute of Development, Aging and\r Cancer, Tohoku University, 4-1 Seiyomachi Aoba-ku, Sendai 980, Japan"}]},{"given":"Brendan","family":"O\u2019Sullivan","sequence":"additional","affiliation":[{"name":"Division of Human Brain Research, Department of Neuroscience, The\r Karolinska Institute, S-171 77 Stockholm, Sweden; Department\r of Psychiatry, Royal Prince Alfred Hospital, Camperdown NSW 2050,\r Sydney, Australia; and Institute of Development, Aging and\r Cancer, Tohoku University, 4-1 Seiyomachi Aoba-ku, Sendai 980, Japan"}]},{"given":"Ryuta","family":"Kawashima","sequence":"additional","affiliation":[{"name":"Division of Human Brain Research, Department of Neuroscience, The\r Karolinska Institute, S-171 77 Stockholm, Sweden; Department\r of Psychiatry, Royal Prince Alfred Hospital, Camperdown NSW 2050,\r Sydney, Australia; and Institute of Development, Aging and\r Cancer, Tohoku University, 4-1 Seiyomachi Aoba-ku, Sendai 980, Japan"}]}],"member":"341","published-online":{"date-parts":[[1998,3,17]]},"reference":[{"key":"e_1_3_4_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0173(87)90018-X"},{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1995.tb00716.x"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1994.tb00255.x"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3932(71)90067-4"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0173(87)90017-8"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.3758\/BF03201532"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.460010103"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.460010303"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1996.tb01186.x"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.1992.127"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/1053-8119(92)90006-9"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(78)90834-X"},{"key":"e_1_3_4_13_2","first-page":"412","volume":"58","author":"Iwamura Y","year":"1985","unstructured":"Y Iwamura, M Tanaka, M Sakamoto, O Hikosaka Exp Brain Res 58, 412\u2013420 (1985).","journal-title":"Exp Brain Res"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00232190"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199407000-00029"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/5.5.429"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199602290-00017"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1991.tb00835.x"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7134982"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1991.66.1.153"},{"key":"e_1_3_4_21_2","first-page":"331","volume":"70","author":"Sinclair R J","year":"1993","unstructured":"R J Sinclair, H Burton J Neurosci 70, 331\u2013350 (1993).","journal-title":"J Neurosci"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.4.1317"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00231849"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903550405"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901920106"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1981.46.6.1260"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902820203"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-05-03821.1995"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.1988.111"},{"key":"e_1_3_4_30_2","first-page":"359","volume":"14","author":"Applegate C N","year":"1988","unstructured":"C N Applegate, P T Fox Soc Neurosci Abstr 14, 359 (1988).","journal-title":"Soc Neurosci Abstr"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.14-07-04095.1994"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2003220"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1991.0048"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1992.tb08055.x"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.3109\/08990229309028839"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.15.030192.001303"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-01-00798.1995"},{"key":"e_1_3_4_38_2","first-page":"549","volume-title":"Analysis of Visual Behavior","author":"Ungerleider L G","year":"1982","unstructured":"L G Ungerleider, M Mishikin Analysis of Visual Behavior, eds D J Ingle, M A Goodale, R J W Mansfield (MIT Press, Cambridge, MA), pp. 549\u2013586 (1982)."},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.3283936"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(88)90130-0"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.16.030193.002101"}],"container-title":["Proceedings of the National Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pnas.org\/doi\/pdf\/10.1073\/pnas.95.6.3295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T20:19:03Z","timestamp":1649881143000},"score":1,"resource":{"primary":{"URL":"https:\/\/pnas.org\/doi\/full\/10.1073\/pnas.95.6.3295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,3,17]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1998,3,17]]}},"alternative-id":["10.1073\/pnas.95.6.3295"],"URL":"https:\/\/doi.org\/10.1073\/pnas.95.6.3295","relation":{},"ISSN":["0027-8424","1091-6490"],"issn-type":[{"value":"0027-8424","type":"print"},{"value":"1091-6490","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,3,17]]},"assertion":[{"value":"1997-10-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1997-12-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1998-03-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}