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Fluorescence\n            <jats:italic>in situ<\/jats:italic>\n            hybridization with centromere, nucleolus organizer region (NOR), and 5S rRNA gene probes reveals the expected numbers of progenitor chromosomes in natural\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>suecica<\/jats:italic>\n            , but one pair of\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>thaliana<\/jats:italic>\n            NORs and one pair of\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>arenosa<\/jats:italic>\n            -derived 5S gene loci are missing. Similarly, in newly formed synthetic\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>suecica<\/jats:italic>\n            -like allotetraploids, pairs of\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>thaliana<\/jats:italic>\n            NORs are gained\n            <jats:italic>de novo<\/jats:italic>\n            , lost, and\/or transposed to\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>arenosa<\/jats:italic>\n            chromosomes, with genotypic differences apparent between F\n            <jats:sub>3<\/jats:sub>\n            siblings of the same F\n            <jats:sub>2<\/jats:sub>\n            parent and between independent lines. Likewise, pairs of\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>arenosa<\/jats:italic>\n            5S genes are lost and novel linkages between 5S loci and NORs arise in synthetic allotetraploids. By contrast, the expected numbers of\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>arenosa<\/jats:italic>\n            -derived NORs and\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>thaliana<\/jats:italic>\n            -derived 5S loci are found in both natural and synthetic\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>suecica<\/jats:italic>\n            . Collectively, these observations suggest that some, but not all, loci are unstable in newly formed\n            <jats:italic>A<\/jats:italic>\n            .\n            <jats:italic>suecica<\/jats:italic>\n            allotetraploids and can participate in a variety of alternative rearrangements, some of which resemble chromosomal changes found in nature.\n          <\/jats:p>","DOI":"10.1073\/pnas.0407258102","type":"journal-article","created":{"date-parts":[[2004,12,17]],"date-time":"2004-12-17T01:24:08Z","timestamp":1103246648000},"page":"18240-18245","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":228,"title":["Chromosomal locus rearrangements are a rapid response to formation of the allotetraploid\n            <i>Arabidopsis suecica<\/i>\n            genome"],"prefix":"10.1073","volume":"101","author":[{"given":"Olga","family":"Pontes","sequence":"first","affiliation":[{"name":"Centro de Bota\u0101nica Aplicada \u00e0 Agricultura, Instituto Superior de Agronomia, Tapada da Ajuda, 1349-017 Lisbon, Portugal; Sec\u00e7\u00e3o Aut\u00f3noma de Biotecnologia, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa, Monte de Caparica, 2829-516 Caparica, Portugal; Department of Biology, Washington University, 1 Brookings Drive, St. Louis, MO 63130; and Department of Biology, University of Washington, Seattle, WA 98195"}]},{"given":"Nuno","family":"Neves","sequence":"additional","affiliation":[{"name":"Centro de Bota\u0101nica Aplicada \u00e0 Agricultura, Instituto Superior de Agronomia, Tapada da Ajuda, 1349-017 Lisbon, Portugal; Sec\u00e7\u00e3o Aut\u00f3noma de Biotecnologia, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa, Monte de Caparica, 2829-516 Caparica, Portugal; Department of Biology, Washington University, 1 Brookings Drive, St. Louis, MO 63130; and Department of Biology, University of Washington, Seattle, WA 98195"}]},{"given":"Manuela","family":"Silva","sequence":"additional","affiliation":[{"name":"Centro de Bota\u0101nica Aplicada \u00e0 Agricultura, Instituto Superior de Agronomia, Tapada da Ajuda, 1349-017 Lisbon, Portugal; Sec\u00e7\u00e3o Aut\u00f3noma de Biotecnologia, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa, Monte de Caparica, 2829-516 Caparica, Portugal; Department of Biology, Washington University, 1 Brookings Drive, St. Louis, MO 63130; and Department of Biology, University of Washington, Seattle, WA 98195"}]},{"given":"Michelle S.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Centro de Bota\u0101nica Aplicada \u00e0 Agricultura, Instituto Superior de Agronomia, Tapada da Ajuda, 1349-017 Lisbon, Portugal; Sec\u00e7\u00e3o Aut\u00f3noma de Biotecnologia, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa, Monte de Caparica, 2829-516 Caparica, Portugal; Department of Biology, Washington University, 1 Brookings Drive, St. Louis, MO 63130; and Department of Biology, University of Washington, Seattle, WA 98195"}]},{"given":"Andreas","family":"Madlung","sequence":"additional","affiliation":[{"name":"Centro de Bota\u0101nica Aplicada \u00e0 Agricultura, Instituto Superior de Agronomia, Tapada da Ajuda, 1349-017 Lisbon, Portugal; Sec\u00e7\u00e3o Aut\u00f3noma de Biotecnologia, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa, Monte de Caparica, 2829-516 Caparica, Portugal; Department of Biology, Washington University, 1 Brookings Drive, St. Louis, MO 63130; and Department of Biology, University of Washington, Seattle, WA 98195"}]},{"given":"Luca","family":"Comai","sequence":"additional","affiliation":[{"name":"Centro de Bota\u0101nica Aplicada \u00e0 Agricultura, Instituto Superior de Agronomia, Tapada da Ajuda, 1349-017 Lisbon, Portugal; Sec\u00e7\u00e3o Aut\u00f3noma de Biotecnologia, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa, Monte de Caparica, 2829-516 Caparica, Portugal; Department of Biology, Washington University, 1 Brookings Drive, St. Louis, MO 63130; and Department of Biology, University of Washington, Seattle, WA 98195"}]},{"given":"Wanda","family":"Viegas","sequence":"additional","affiliation":[{"name":"Centro de Bota\u0101nica Aplicada \u00e0 Agricultura, Instituto Superior de Agronomia, Tapada da Ajuda, 1349-017 Lisbon, Portugal; Sec\u00e7\u00e3o Aut\u00f3noma de Biotecnologia, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa, Monte de Caparica, 2829-516 Caparica, Portugal; Department of Biology, Washington University, 1 Brookings Drive, St. Louis, MO 63130; and Department of Biology, University of Washington, Seattle, WA 98195"}]},{"given":"Craig S.","family":"Pikaard","sequence":"additional","affiliation":[{"name":"Centro de Bota\u0101nica Aplicada \u00e0 Agricultura, Instituto Superior de Agronomia, Tapada da Ajuda, 1349-017 Lisbon, Portugal; Sec\u00e7\u00e3o Aut\u00f3noma de Biotecnologia, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa, Monte de Caparica, 2829-516 Caparica, Portugal; Department of Biology, Washington University, 1 Brookings Drive, St. Louis, MO 63130; and Department of Biology, University of Washington, Seattle, WA 98195"}]}],"member":"341","published-online":{"date-parts":[[2004,12,16]]},"reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.264.5157.421"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1360-1385(97)01154-0"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-5347(99)01638-9"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006480722854"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5223.1968.tb02169.x"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/42711"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(96)01351-8"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/35048692"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.13.7008"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/35072009"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a026112"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.1.280"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.8.5.479"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00265054"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.17.7719"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msh140"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.1993.181"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-9525(01)02545-8"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-9525(03)00015-5"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.2174\/1389202023350255"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(01)00556-5"},{"key":"e_1_3_2_22_2","first-page":"1735","volume":"13","year":"2001","unstructured":"Ozkan, H., Levy, A. 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