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From the ancestral NK gene cluster, only the Tlx\u2013Lbx and NK3\u2013NK4 linkages have been retained in chordates. This evolutionary pattern is in marked contrast to the Hox and ParaHox gene clusters, which are compact in amphioxus and vertebrates, but have been disrupted in\n            <jats:italic>Drosophila<\/jats:italic>\n            .\n          <\/jats:p>","DOI":"10.1073\/pnas.0836141100","type":"journal-article","created":{"date-parts":[[2003,4,29]],"date-time":"2003-04-29T16:23:56Z","timestamp":1051633436000},"page":"5292-5295","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":76,"title":["Dispersal of NK homeobox gene clusters in amphioxus and humans"],"prefix":"10.1073","volume":"100","author":[{"given":"Graham N.","family":"Luke","sequence":"first","affiliation":[{"name":"School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, United Kingdom; Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; and The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom"}]},{"given":"L. Filipe C.","family":"Castro","sequence":"additional","affiliation":[{"name":"School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, United Kingdom; Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; and The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom"}]},{"given":"Kirsten","family":"McLay","sequence":"additional","affiliation":[{"name":"School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, United Kingdom; Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; and The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom"}]},{"given":"Christine","family":"Bird","sequence":"additional","affiliation":[{"name":"School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, United Kingdom; Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; and The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom"}]},{"given":"Alan","family":"Coulson","sequence":"additional","affiliation":[{"name":"School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, United Kingdom; Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom; and The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom"}]},{"given":"Peter W. 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