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By capturing the world's second-deepest known fish, the hadal snailfish\n                    <jats:italic>Notoliparis kermadecensis<\/jats:italic>\n                    from 7,000 m, we find that they have the highest recorded TMAO contents, which, moreover, yield an extrapolated maximum for fish at about 8,200 m. This is previously unidentified evidence that biochemistry may constrain depth for a large taxonomic group.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1322003111","type":"journal-article","created":{"date-parts":[[2014,3,3]],"date-time":"2014-03-03T21:26:27Z","timestamp":1393881987000},"page":"4461-4465","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":271,"title":["Marine fish may be biochemically constrained from inhabiting the deepest ocean depths"],"prefix":"10.1073","volume":"111","author":[{"given":"Paul H.","family":"Yancey","sequence":"first","affiliation":[{"name":"Biology Department, Whitman College, Walla Walla, WA 99362;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mackenzie E.","family":"Gerringer","sequence":"additional","affiliation":[{"name":"Biology Department, Whitman College, Walla Walla, WA 99362;"},{"name":"Department of Oceanography, University of Hawaii, Honolulu, HI 96822;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey C.","family":"Drazen","sequence":"additional","affiliation":[{"name":"Department of Oceanography, University of Hawaii, Honolulu, HI 96822;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley A.","family":"Rowden","sequence":"additional","affiliation":[{"name":"National Institute of Water and Atmospheric Research, Wellington 6021, New Zealand; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Jamieson","sequence":"additional","affiliation":[{"name":"Oceanlab, Institute of Biological and Environmental Sciences, University of Aberdeen, Newburgh, Aberdeenshire AB41 6AA, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2014,3,3]]},"reference":[{"key":"e_1_3_3_1_2","first-page":"211","article-title":"Zonation of deep biota on continental margins","volume":"43","author":"Carney RS","year":"2005","unstructured":"RS Carney, Zonation of deep biota on continental margins. 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