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Furthermore, we established strategies for reducing the hallucinogenic and cardiotoxic potential of LSD and identified\n                    <jats:bold>UCD0094<\/jats:bold>\n                    and\n                    <jats:bold>UCD0076<\/jats:bold>\n                    as ergologs with improved safety profiles. In stark contrast to LSD,\n                    <jats:bold>UCD0076<\/jats:bold>\n                    exhibits preference for activating 5-HT2C receptors over other 5-HT2 receptors and produces antipsychotic-like properties in mouse behavioral assays.\n                  <\/jats:p>","DOI":"10.1073\/pnas.2603412123","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T17:47:55Z","timestamp":1788889675000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":0,"title":["Deconstruction of lysergic acid diethylamide"],"prefix":"10.1073","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3337-9785","authenticated-orcid":false,"given":"Andrian G.","family":"Basargin","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05rrcem69","id-type":"ROR","asserted-by":"publisher"}],"name":"Institute for Psychedelics and Neurotherapeutics, University of 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