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The major orogenic belts of the Asian continent, including the Central Asian, Tethyan, and Alpine\u2013Himalayan belts, which record extensive subduction processes, offer an ideal target to address the hydration of the MTZ and its relationship with subduction. Here, we map water content at the MTZ base by combining mineral physics constraints on hydrous pyrolite and global seismic observations of velocity structure and 660-km discontinuity topography. Our results indicate an average global water content of approximately 0.14 wt%, with pronounced hydration anomalies in parts of Asia. Linking these anomalies with reconstructions of past subduction events since 410 Ma reveals extensive water delivery to the MTZ, particularly beneath parts of the Mongol\u2013Okhotsk suture zone, the Central Asian Orogenic Belt, and the Tethyan orogenic domain, where water content exceeds 0.5 wt%. These results connect ancient subduction history to present-day mantle hydration, offering insights into Earth\u2019s deep water cycle.<\/jats:p>","DOI":"10.1073\/pnas.2622030123","type":"journal-article","created":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:37:18Z","timestamp":1793295438000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":0,"title":["Hydration at the base of the mantle transition zone by ancient subductions in Asia"],"prefix":"10.1073","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0102-1420","authenticated-orcid":false,"given":"Jiyu","family":"Liu","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04c4dkn09","id-type":"ROR","asserted-by":"publisher"}],"name":"State Key Laboratory of Precision Geodesy, School of Earth and Space Sciences, University of Science and Technology of China","place":["Hefei, 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