{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T11:55:08Z","timestamp":1774353308385,"version":"3.50.1"},"reference-count":87,"publisher":"Elsevier BV","issue":"38","license":[{"start":{"date-parts":[[2000,9,1]],"date-time":"2000-09-01T00:00:00Z","timestamp":967766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,4]],"date-time":"2020-10-04T00:00:00Z","timestamp":1601769600000},"content-version":"vor","delay-in-days":7338,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2000,9]]},"DOI":"10.1074\/jbc.m003174200","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T15:10:36Z","timestamp":1027696236000},"page":"29466-29476","source":"Crossref","is-referenced-by-count":105,"title":["Pemphigus Vulgaris Antibody Identifies Pemphaxin"],"prefix":"10.1016","volume":"275","author":[{"given":"Vu Thuong","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assane","family":"Ndoye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergei A.","family":"Grando","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M003174200_bib1","series-title":"Lever's Histopathology of the Skin","first-page":"209","author":"Cohen","year":"1997"},{"key":"10.1074\/jbc.M003174200_bib2","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S1079-2104(97)90030-5","volume":"84","author":"Robinson","year":"1997","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod."},{"key":"10.1074\/jbc.M003174200_bib3","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1001\/archderm.1976.01630310024005","volume":"112","author":"Rosenberg","year":"1976","journal-title":"Arch. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib4","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0190-9622(82)70111-2","volume":"7","author":"Ahmed","year":"1982","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib5","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1001\/archderm.134.8.971","volume":"134","author":"Nguyen","year":"1998","journal-title":"Arch. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib6","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1172\/JCI110615","volume":"70","author":"Stanley","year":"1982","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M003174200_bib7","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1172\/JCI111426","volume":"74","author":"Stanley","year":"1984","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M003174200_bib8","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1056\/NEJM198205203062001","volume":"306","author":"Anhalt","year":"1982","journal-title":"N. Engl. J. Med."},{"key":"10.1074\/jbc.M003174200_bib9","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0092-8674(91)90360-B","volume":"67","author":"Amagai","year":"1991","journal-title":"Cell"},{"key":"10.1074\/jbc.M003174200_bib10","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1172\/JCI115968","volume":"90","author":"Amagai","year":"1992","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M003174200_bib11","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/1523-1747.ep12340663","volume":"106","author":"Memar","year":"1996","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib12","series-title":"Characterization of the Pemphigus Vulgaris Anbtigen (Desmoglein 3) Expressed in Insect Cells: Induction of Blister-Causing Antibodies","author":"Memar","year":"1995"},{"key":"10.1074\/jbc.M003174200_bib13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1172\/JCI117349","volume":"94","author":"Amagai","year":"1994","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M003174200_bib14","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1172\/JCI3647","volume":"102","author":"Amagai","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M003174200_bib15","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1172\/JCI5252","volume":"103","author":"Mahoney","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M003174200_bib16","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1001\/jama.282.6.572","volume":"282","author":"Udey","year":"1999","journal-title":"J. Am. Med. Assoc."},{"key":"10.1074\/jbc.M003174200_bib17","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1046\/j.1523-1747.1999.00585.x","volume":"112","author":"Ding","year":"1999","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib18","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1083\/jcb.137.5.1091","volume":"137","author":"Koch","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M003174200_bib19","unstructured":"Nguyen, V. T., Ndoye, A., and Grando, S. A. (2000)Am. J. Pathol., in press."},{"key":"10.1074\/jbc.M003174200_bib20","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1468-3083.1993.tb00016.x","volume":"2","author":"Grando","year":"1993","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1074\/jbc.M003174200_bib21","first-page":"262","volume":"4","author":"Grando","year":"1997","journal-title":"Curr. Opin. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib22","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/jidsymp.1997.10","volume":"2","author":"Grando","year":"1997","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"key":"10.1074\/jbc.M003174200_bib23","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1365-4362.1985.tb05507.x","volume":"24","author":"Beutner","year":"1985","journal-title":"Int. J. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib24","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1365-2230.1995.tb01376.x","volume":"20","author":"Ohata","year":"1995","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib25","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/1523-1747.ep12471811","volume":"100","author":"Nguyen","year":"1993","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib26","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1159\/000211098","volume":"6","author":"Grando","year":"1993","journal-title":"Skin Pharmacol."},{"key":"10.1074\/jbc.M003174200_bib27","series-title":"DNA Cloning: A Practical Approach","first-page":"49","author":"Huynh","year":"1985"},{"key":"10.1074\/jbc.M003174200_bib28","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0014-2999(75)90055-2","volume":"31","author":"Taylor","year":"1975","journal-title":"Eur. J. Pharmacol."},{"key":"10.1074\/jbc.M003174200_bib29","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1046\/j.1523-1747.2000.00835.x","volume":"114","author":"Feliciani","year":"2000","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib30","doi-asserted-by":"crossref","first-page":"522","DOI":"10.4049\/jimmunol.164.1.522","volume":"164","author":"Toto","year":"2000","journal-title":"J. Immunol."},{"key":"10.1074\/jbc.M003174200_bib31","doi-asserted-by":"crossref","first-page":"8125","DOI":"10.1093\/nar\/15.20.8125","volume":"15","author":"Kozak","year":"1987","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M003174200_bib32","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1042\/bj2980553","volume":"298","author":"Jost","year":"1994","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M003174200_bib33","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1432-1033.1992.tb17125.x","volume":"207","author":"Jost","year":"1992","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M003174200_bib34","doi-asserted-by":"crossref","first-page":"13993","DOI":"10.1016\/S0021-9258(19)49668-3","volume":"267","author":"Jones","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M003174200_bib35","first-page":"307","volume":"35","author":"Zimmerman","year":"1995","journal-title":"Biochem. Mol. Biol. Int."},{"key":"10.1074\/jbc.M003174200_bib36","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0021-9258(17)31284-X","volume":"264","author":"Curtis","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M003174200_bib37","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/S1357-2725(97)00057-5","volume":"29","author":"Siever","year":"1997","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1074\/jbc.M003174200_bib38","first-page":"9","volume":"107 Suppl. 1","author":"Lin","year":"1997","journal-title":"Clin. Exp. Immunol."},{"key":"10.1074\/jbc.M003174200_bib39","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3109\/08916938908997095","volume":"3","author":"Grando","year":"1989","journal-title":"Autoimmunity"},{"key":"10.1074\/jbc.M003174200_bib40","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/1523-1747.ep12277087","volume":"92","author":"Hashimoto","year":"1989","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib41","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/1523-1747.ep12709624","volume":"92","author":"Kawana","year":"1989","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib42","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1001\/archderm.1989.01670190059006","volume":"125","author":"Grando","year":"1989","journal-title":"Arch. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib43","first-page":"137","volume":"32","author":"Grando","year":"1990","journal-title":"J. Clin. Lab. Immunol."},{"key":"10.1074\/jbc.M003174200_bib44","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0923-1811(99)00016-X","volume":"20","author":"Amagai","year":"1999","journal-title":"J. Dermatol. Sci."},{"key":"10.1074\/jbc.M003174200_bib45","first-page":"107","volume":"189","author":"Stanley","year":"1995","journal-title":"Ciba Found. Symp."},{"key":"10.1074\/jbc.M003174200_bib46","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/1523-1747.ep12470554","volume":"89","author":"Kitajima","year":"1987","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib47","doi-asserted-by":"crossref","first-page":"6228","DOI":"10.4049\/jimmunol.163.11.6228","volume":"163","author":"Fan","year":"1999","journal-title":"J. Immunol."},{"key":"10.1074\/jbc.M003174200_bib48","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1172\/JCI8748","volume":"105","author":"Amagai","year":"2000","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M003174200_bib49","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1365-2133.1995.tb02617.x","volume":"133","author":"Iwatsuki","year":"1995","journal-title":"Br. J. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib50","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1083\/jcb.122.2.409","volume":"122","author":"Karpati","year":"1993","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M003174200_bib51","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1083\/jcb.132.3.451","volume":"132","author":"Rajasekaran","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M003174200_bib52","doi-asserted-by":"crossref","first-page":"10904","DOI":"10.1074\/jbc.271.18.10904","volume":"271","author":"Witcher","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M003174200_bib53","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1242\/jcs.110.3.311","volume":"110","author":"Fujimoto","year":"1997","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M003174200_bib54","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1126\/science.1439804","volume":"258","author":"Creutz","year":"1992","journal-title":"Science"},{"key":"10.1074\/jbc.M003174200_bib55","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0168-9525(94)90171-6","volume":"10","author":"Smith","year":"1994","journal-title":"Trends Genet."},{"key":"10.1074\/jbc.M003174200_bib56","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1007\/s000180050064","volume":"53","author":"Morgan","year":"1997","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1074\/jbc.M003174200_bib57","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/0968-0004(94)90002-7","volume":"19","author":"Demange","year":"1994","journal-title":"Trends Biochem. Sci."},{"key":"10.1074\/jbc.M003174200_bib58","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0962-8924(96)10049-0","volume":"7","author":"Moss","year":"1997","journal-title":"Trends Cell Biol."},{"key":"10.1074\/jbc.M003174200_bib59","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s000180050068","volume":"53","author":"Donnelly","year":"1997","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1074\/jbc.M003174200_bib60","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/s000180050067","volume":"53","author":"Reutelingsperger","year":"1997","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1074\/jbc.M003174200_bib61","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1111\/1523-1747.ep12371684","volume":"101","author":"Fava","year":"1993","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib62","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1111\/1523-1747.ep12499850","volume":"98","author":"Culard","year":"1992","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib63","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1007\/BF02505262","volume":"288","author":"Ma","year":"1996","journal-title":"Arch. Dermatol. Res."},{"key":"10.1074\/jbc.M003174200_bib64","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1242\/jcs.109.1.247","volume":"109","author":"Barwise","year":"1996","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M003174200_bib65","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1083\/jcb.126.2.539","volume":"126","author":"Chung","year":"1994","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M003174200_bib66","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0092-8674(00)81559-7","volume":"100","author":"Vasioukhin","year":"2000","journal-title":"Cell"},{"key":"10.1074\/jbc.M003174200_bib67","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1111\/j.1432-1033.1994.tb19067.x","volume":"223","author":"Nakao","year":"1994","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M003174200_bib68","first-page":"412","volume":"9","author":"Falcone","year":"1995","journal-title":"FASEB J."},{"key":"10.1074\/jbc.M003174200_bib69","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1749-6632.1997.tb52013.x","volume":"811","author":"Hajjar","year":"1997","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1074\/jbc.M003174200_bib70","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s000180050069","volume":"53","author":"Von Der Mark","year":"1997","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1074\/jbc.M003174200_bib71","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1091\/mbc.7.6.883","volume":"7","author":"Chung","year":"1996","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M003174200_bib72","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1365-2133.1995.tb02486.x","volume":"133","author":"Schenk","year":"1995","journal-title":"Br. J. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib73","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1016\/0006-2952(88)90037-8","volume":"37","author":"Ulus","year":"1988","journal-title":"Biochem. Pharmacol."},{"key":"10.1074\/jbc.M003174200_bib74","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0006-8993(86)91551-9","volume":"385","author":"Sterz","year":"1986","journal-title":"Brain Res."},{"key":"10.1074\/jbc.M003174200_bib75","doi-asserted-by":"crossref","first-page":"20887","DOI":"10.1016\/S0021-9258(17)45299-9","volume":"265","author":"van Koppen","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M003174200_bib76","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1042\/bj2850753","volume":"285","author":"Matus-Leibovitch","year":"1992","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M003174200_bib77","doi-asserted-by":"crossref","first-page":"25506","DOI":"10.1074\/jbc.271.41.25506","volume":"271","author":"Shtrom","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M003174200_bib78","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/1523-1747.ep12273480","volume":"83","author":"Patel","year":"1984","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib79","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/sj.jidsp.5640197","volume":"4","author":"Kitajima","year":"1999","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"key":"10.1074\/jbc.M003174200_bib80","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/jcb.240530311","volume":"53","author":"Tressler","year":"1993","journal-title":"J. Cell. Biochem."},{"key":"10.1074\/jbc.M003174200_bib81","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1093\/hmg\/8.6.971","volume":"8","author":"Rickman","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M003174200_bib82","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1046\/j.1523-1747.1999.00783.x","volume":"113","author":"Whittock","year":"1999","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib83","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/hmg\/8.1.143","volume":"8","author":"Armstrong","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M003174200_bib84","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/71701","volume":"24","author":"Hu","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M003174200_bib85","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/6784","volume":"21","author":"Sakuntabhai","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M003174200_bib86","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/1523-1747.ep12365541","volume":"101","author":"Bastian","year":"1993","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M003174200_bib87","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/1523-1747.ep12518278","volume":"81","author":"Swanson","year":"1983","journal-title":"J. Invest. Dermatol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819794265?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819794265?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M003174200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T06:22:46Z","timestamp":1704349366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819794265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,9]]},"references-count":87,"journal-issue":{"issue":"38","published-print":{"date-parts":[[2000,9]]}},"alternative-id":["S0021925819794265"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m003174200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2000,9]]}}}