{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T21:55:13Z","timestamp":1783634113301,"version":"3.55.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"43","license":[{"start":{"date-parts":[[2001,10,1]],"date-time":"2001-10-01T00:00:00Z","timestamp":1001894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"vor","delay-in-days":6940,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2001,10]]},"DOI":"10.1074\/jbc.m105391200","type":"journal-article","created":{"date-parts":[[2014,6,11]],"date-time":"2014-06-11T11:42:17Z","timestamp":1402486937000},"page":"40346-40352","source":"Crossref","is-referenced-by-count":49,"title":["The Von Hippel-Lindau Protein Interacts with Heteronuclear Ribonucleoprotein A2 and Regulates Its Expression"],"prefix":"10.1016","volume":"276","author":[{"given":"Patricia A.","family":"Pioli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William F.C.","family":"Rigby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M105391200_bib1","series-title":"Mendelian Inheritance in Man","author":"McKusick","year":"1992"},{"key":"10.1074\/jbc.M105391200_bib2","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/humu.1380050109","volume":"5","author":"Chen","year":"1995","journal-title":"Hum. Mutat."},{"key":"10.1074\/jbc.M105391200_bib3","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/BF00218913","volume":"93","author":"Crossey","year":"1994","journal-title":"Hum. Genet."},{"key":"10.1074\/jbc.M105391200_bib4","first-page":"1092","volume":"55","author":"Whaley","year":"1994","journal-title":"Am. J. Hum. Genet."},{"key":"10.1074\/jbc.M105391200_bib5","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1093\/jnci\/81.14.1097","volume":"81","author":"Tory","year":"1989","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1074\/jbc.M105391200_bib6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/ng0594-85","volume":"7","author":"Gnarra","year":"1994","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M105391200_bib7","first-page":"2852","volume":"54","author":"Shuin","year":"1994","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M105391200_bib8","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1073\/pnas.68.4.820","volume":"68","author":"Knudson","year":"1971","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib9","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1126\/science.8493574","volume":"260","author":"Latif","year":"1993","journal-title":"Science"},{"key":"10.1074\/jbc.M105391200_bib10","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/nm0895-822","volume":"1","author":"Iliopoulos","year":"1995","journal-title":"Nat. Med."},{"key":"10.1074\/jbc.M105391200_bib11","doi-asserted-by":"crossref","first-page":"11661","DOI":"10.1073\/pnas.95.20.11661","volume":"95","author":"Iliopoulos","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib12","doi-asserted-by":"crossref","first-page":"8817","DOI":"10.1073\/pnas.95.15.8817","volume":"95","author":"Schoenfeld","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib13","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1038\/sj.onc.1202473","volume":"18","author":"Blankenship","year":"1999","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M105391200_bib14","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1126\/science.7660122","volume":"269","author":"Duan","year":"1995","journal-title":"Science"},{"key":"10.1074\/jbc.M105391200_bib15","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1073\/pnas.93.5.1770","volume":"93","author":"Lee","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib16","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1128\/MCB.19.2.1486","volume":"19","author":"Lee","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M105391200_bib17","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S0046-8177(97)90035-6","volume":"28","author":"Corless","year":"1997","journal-title":"Hum. Path."},{"key":"10.1074\/jbc.M105391200_bib18","first-page":"231","volume":"75","author":"Los","year":"1996","journal-title":"Lab. Invest."},{"key":"10.1074\/jbc.M105391200_bib19","doi-asserted-by":"crossref","first-page":"8991","DOI":"10.1074\/jbc.275.12.8991","volume":"275","author":"Groulx","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M105391200_bib20","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1126\/science.7660130","volume":"269","author":"Kibel","year":"1995","journal-title":"Science"},{"key":"10.1074\/jbc.M105391200_bib21","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1128\/MCB.18.2.732","volume":"18","author":"Lonergan","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M105391200_bib22","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1073\/pnas.94.6.2156","volume":"94","author":"Pause","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib23","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1126\/science.284.5414.657","volume":"284","author":"Kamura","year":"1999","journal-title":"Science"},{"key":"10.1074\/jbc.M105391200_bib24","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S1357-4310(99)01481-1","volume":"5","author":"Ohh","year":"1999","journal-title":"Mol. Med. Today"},{"key":"10.1074\/jbc.M105391200_bib25","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1126\/science.284.5413.455","volume":"284","author":"Stebbins","year":"1999","journal-title":"Science"},{"key":"10.1074\/jbc.M105391200_bib26","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0092-8674(00)80098-7","volume":"86","author":"Bai","year":"1996","journal-title":"Cell"},{"key":"10.1074\/jbc.M105391200_bib27","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0092-8674(00)80118-X","volume":"86","author":"Willems","year":"1996","journal-title":"Cell"},{"key":"10.1074\/jbc.M105391200_bib28","doi-asserted-by":"crossref","first-page":"6634","DOI":"10.1128\/MCB.16.12.6634","volume":"16","author":"Mathias","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M105391200_bib29","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/S0960-9822(96)00697-5","volume":"6","author":"Jackson","year":"1996","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M105391200_bib30","doi-asserted-by":"crossref","first-page":"12436","DOI":"10.1073\/pnas.96.22.12436","volume":"96","author":"Iwai","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib31","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1101\/gad.13.14.1822","volume":"13","author":"Listzwan","year":"1999","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M105391200_bib32","doi-asserted-by":"crossref","first-page":"10430","DOI":"10.1073\/pnas.190332597","volume":"97","author":"Kamura","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib33","doi-asserted-by":"crossref","first-page":"10595","DOI":"10.1073\/pnas.93.20.10595","volume":"93","author":"Iliopoulos","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib34","doi-asserted-by":"crossref","first-page":"10589","DOI":"10.1073\/pnas.93.20.10589","volume":"93","author":"Gnarra","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib35","first-page":"1358","volume":"55","author":"Wizigmann-Voos","year":"1995","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M105391200_bib36","doi-asserted-by":"crossref","first-page":"71","DOI":"10.7326\/0003-4819-95-1-71","volume":"95","author":"Golde","year":"1981","journal-title":"Ann. Intern. Med."},{"key":"10.1074\/jbc.M105391200_bib37","first-page":"2299","volume":"56","author":"Siemeister","year":"1996","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M105391200_bib38","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1097\/00005072-199711000-00009","volume":"56","author":"Stratmann","year":"1997","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1074\/jbc.M105391200_bib39","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1152\/physrev.1996.76.3.839","volume":"76","author":"Bunn","year":"1996","journal-title":"Physiol. Rev."},{"key":"10.1074\/jbc.M105391200_bib40","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1023\/A:1022446730452","volume":"29","author":"Dang","year":"1997","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1074\/jbc.M105391200_bib41","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/28867","volume":"394","author":"Carmeliet","year":"1998","journal-title":"Nature"},{"key":"10.1074\/jbc.M105391200_bib42","doi-asserted-by":"crossref","first-page":"7987","DOI":"10.1073\/pnas.95.14.7987","volume":"95","author":"Huang","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib43","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0092-8674(00)80108-7","volume":"86","author":"Hanahan","year":"1996","journal-title":"Cell"},{"key":"10.1074\/jbc.M105391200_bib44","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/35017054","volume":"2","author":"Ohh","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M105391200_bib45","doi-asserted-by":"crossref","first-page":"25733","DOI":"10.1074\/jbc.M002740200","volume":"275","author":"Cockman","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M105391200_bib46","doi-asserted-by":"crossref","first-page":"5363","DOI":"10.1128\/MCB.15.10.5363","volume":"15","author":"Stein","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M105391200_bib47","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/20459","volume":"399","author":"Maxwell","year":"1999","journal-title":"Nature"},{"key":"10.1074\/jbc.M105391200_bib48","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/0092-8674(86)90341-7","volume":"46","author":"Shaw","year":"1986","journal-title":"Cell"},{"key":"10.1074\/jbc.M105391200_bib49","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1006\/bbrc.1999.1040","volume":"261","author":"Hamilton","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M105391200_bib50","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1002\/j.1460-2075.1994.tb06369.x","volume":"13","author":"Burd","year":"1994","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M105391200_bib51","doi-asserted-by":"crossref","first-page":"8881","DOI":"10.1016\/S0021-9258(18)52955-0","volume":"268","author":"Hamilton","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M105391200_bib52","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1093\/nar\/11.5.1475","volume":"11","author":"Dignam","year":"1983","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M105391200_bib53","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1074\/jbc.M105391200_bib54","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M105391200_bib55","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/0003-2697(83)90418-9","volume":"132","author":"Feinberg","year":"1983","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M105391200_bib56","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1128\/MCB.21.3.865-874.2001","volume":"21","author":"Davidowitz","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M105391200_bib57","first-page":"4957","volume":"58","author":"Lieubeau-Teillet","year":"1998","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M105391200_bib58","doi-asserted-by":"crossref","first-page":"6331","DOI":"10.1128\/MCB.15.11.6331","volume":"15","author":"Curatola","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M105391200_bib59","doi-asserted-by":"crossref","first-page":"8507","DOI":"10.1073\/pnas.97.15.8507","volume":"97","author":"Schoenfeld","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M105391200_bib60","doi-asserted-by":"crossref","first-page":"4298","DOI":"10.1093\/emboj\/19.16.4298","volume":"19","author":"Tanimoto","year":"2000","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M105391200_bib61","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1074\/jbc.274.3.1359","volume":"274","author":"Shih","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M105391200_bib62","doi-asserted-by":"crossref","first-page":"25492","DOI":"10.1074\/jbc.271.41.25492","volume":"271","author":"Levy","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M105391200_bib63","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S0169-328X(98)00121-1","volume":"58","author":"Tsukamoto","year":"1998","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1074\/jbc.M105391200_bib64","first-page":"2237","volume":"8","author":"Swanson","year":"1988","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M105391200_bib65","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1006\/excr.1998.4323","volume":"246","author":"Kamma","year":"1999","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M105391200_bib66","doi-asserted-by":"crossref","first-page":"10760","DOI":"10.1074\/jbc.271.18.10760","volume":"271","author":"Zhou","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M105391200_bib67","first-page":"2237","volume":"3","author":"Tockman","year":"1997","journal-title":"Clin. Cancer Res."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192582060117X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192582060117X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M105391200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T02:42:09Z","timestamp":1639708929000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002192582060117X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,10]]},"references-count":67,"journal-issue":{"issue":"43","published-print":{"date-parts":[[2001,10]]}},"alternative-id":["S002192582060117X"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m105391200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2001,10]]}}}