{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T23:23:09Z","timestamp":1770506589123,"version":"3.49.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"14","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T00:00:00Z","timestamp":1601596800000},"content-version":"vor","delay-in-days":5298,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1074\/jbc.m513265200","type":"journal-article","created":{"date-parts":[[2006,1,24]],"date-time":"2006-01-24T01:43:21Z","timestamp":1138067001000},"page":"9346-9350","source":"Crossref","is-referenced-by-count":235,"title":["Rapid Activation of ATR by Ionizing Radiation Requires ATM and Mre11"],"prefix":"10.1016","volume":"281","author":[{"given":"Jeremy S.","family":"Myers","sequence":"first","affiliation":[]},{"given":"David","family":"Cortez","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1074\/jbc.M513265200_bib1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.cell.2004.06.023","volume":"118","author":"Bakkenist","year":"2004","journal-title":"Cell"},{"key":"10.1074\/jbc.M513265200_bib2","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0959-437X(00)00159-3","volume":"11","author":"Shiloh","year":"2001","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1074\/jbc.M513265200_bib3","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1146\/annurev.biochem.73.011303.073723","volume":"73","author":"Sancar","year":"2004","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.M513265200_bib4","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1101\/gad.14.12.1448","volume":"14","author":"Liu","year":"2000","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M513265200_bib5","doi-asserted-by":"crossref","first-page":"4129","DOI":"10.1128\/MCB.21.13.4129-4139.2001","volume":"21","author":"Zhao","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M513265200_bib6","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1126\/science.1065521","volume":"294","author":"Cortez","year":"2001","journal-title":"Science"},{"key":"10.1074\/jbc.M513265200_bib7","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1126\/science.1083430","volume":"300","author":"Zou","year":"2003","journal-title":"Science"},{"key":"10.1074\/jbc.M513265200_bib8","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1101\/gad.1301205","volume":"19","author":"Byun","year":"2005","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M513265200_bib9","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1091\/mbc.e04-11-1006","volume":"16","author":"Ball","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M513265200_bib10","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S1097-2765(02)00507-5","volume":"9","author":"Rouse","year":"2002","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M513265200_bib11","doi-asserted-by":"crossref","first-page":"6673","DOI":"10.1073\/pnas.102167799","volume":"99","author":"Unsal-Kacmaz","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M513265200_bib12","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1128\/MCB.24.3.1292-1300.2003","volume":"24","author":"Unsal-Kacmaz","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M513265200_bib13","doi-asserted-by":"crossref","first-page":"13346","DOI":"10.1074\/jbc.M311098200","volume":"279","author":"Bomgarden","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M513265200_bib14","doi-asserted-by":"crossref","first-page":"38355","DOI":"10.1074\/jbc.M508673200","volume":"280","author":"Kim","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M513265200_bib15","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/nature03442","volume":"434","author":"Falck","year":"2005","journal-title":"Nature"},{"key":"10.1074\/jbc.M513265200_bib16","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nature01368","volume":"421","author":"Bakkenist","year":"2003","journal-title":"Nature"},{"key":"10.1074\/jbc.M513265200_bib17","doi-asserted-by":"crossref","first-page":"5612","DOI":"10.1093\/emboj\/cdg541","volume":"22","author":"Uziel","year":"2003","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M513265200_bib18","first-page":"5054","volume":"54","author":"Canman","year":"1994","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M513265200_bib19","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/0092-8674(93)90496-D","volume":"75","author":"Lu","year":"1993","journal-title":"Cell"},{"key":"10.1074\/jbc.M513265200_bib20","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1101\/gad.13.2.152","volume":"13","author":"Tibbetts","year":"1999","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M513265200_bib21","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/emboj\/17.1.159","volume":"17","author":"Cliby","year":"1998","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M513265200_bib22","doi-asserted-by":"crossref","first-page":"4419","DOI":"10.1128\/MCB.22.12.4419-4432.2002","volume":"22","author":"Xu","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M513265200_bib23","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1101\/gad.1067403","volume":"17","author":"Brown","year":"2003","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M513265200_bib24","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1101\/gad.851000","volume":"14","author":"Tibbetts","year":"2000","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M513265200_bib25","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1101\/gad.14.8.927","volume":"14","author":"Wang","year":"2000","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M513265200_bib26","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/sj.emboj.7600504","volume":"24","author":"Stiff","year":"2005","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M513265200_bib27","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1093\/hmg\/ddi302","volume":"14","author":"Zhong","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M513265200_bib28","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1038\/sj.emboj.7600113","volume":"23","author":"Pichierri","year":"2004","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M513265200_bib29","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1101\/gad.1316905","volume":"19","author":"Cortez","year":"2005","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M513265200_bib30","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1126\/science.1108297","volume":"308","author":"Lee","year":"2005","journal-title":"Science"},{"key":"10.1074\/jbc.M513265200_bib31","doi-asserted-by":"crossref","first-page":"6610","DOI":"10.1093\/emboj\/cdg630","volume":"22","author":"Carson","year":"2003","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M513265200_bib32","first-page":"8554","volume":"61","author":"Wang","year":"2001","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M513265200_bib33","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1093\/nar\/gkh265","volume":"32","author":"Block","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M513265200_bib34","doi-asserted-by":"crossref","first-page":"4345","DOI":"10.1038\/sj.emboj.7600896","volume":"24","author":"Garcia-Muse","year":"2005","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M513265200_bib35","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/nature04148","volume":"438","author":"Tsukuda","year":"2005","journal-title":"Nature"},{"key":"10.1074\/jbc.M513265200_bib36","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/ncb1337","volume":"8","author":"Jazayeri","year":"2005","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M513265200_bib37","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S1097-2765(01)00294-5","volume":"8","author":"Costanzo","year":"2001","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M513265200_bib38","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/sj.onc.1201319","volume":"15","author":"Ziv","year":"1997","journal-title":"Oncogene"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819564687?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819564687?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M513265200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,2]],"date-time":"2022-01-02T22:24:05Z","timestamp":1641162245000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819564687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":38,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["S0021925819564687"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m513265200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}