{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:21:48Z","timestamp":1791091308007,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[1995,3,1]],"date-time":"1995-03-01T00:00:00Z","timestamp":794016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"vor","delay-in-days":9368,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1995,3]]},"DOI":"10.1074\/jbc.270.13.7717","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:53:54Z","timestamp":1027695234000},"page":"7717-7723","source":"Crossref","is-referenced-by-count":228,"title":["Purification and Characterization of a Naturally Occurring Vascular Endothelial Growth Factor \u00b7 Placenta Growth Factor Heterodimer"],"prefix":"10.1016","volume":"270","author":[{"given":"Jerry","family":"DiSalvo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marvin L.","family":"Bayne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Conn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perry W.","family":"Kwok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant G.","family":"Trivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis D.","family":"Soderman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Palisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth A.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.270.13.7717_bib1","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1126\/science.2432664","volume":"235","author":"Folkman","year":"1987","journal-title":"Science"},{"key":"10.1074\/jbc.270.13.7717_bib2","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1172\/JCI114322","volume":"84","author":"Connolly","year":"1989","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.270.13.7717_bib3","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/0006-291X(89)92678-8","volume":"161","author":"Ferrara","year":"1989","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.270.13.7717_bib4","doi-asserted-by":"crossref","first-page":"7311","DOI":"10.1073\/pnas.86.19.7311","volume":"86","author":"Gospodarowicz","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.13.7717_bib5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3109\/08977198909069077","volume":"2","author":"Levy","year":"1989","journal-title":"Growth Factors"},{"key":"10.1074\/jbc.270.13.7717_bib6","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1073\/pnas.87.4.1323","volume":"87","author":"Conn","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.13.7717_bib7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3109\/08977199009011010","volume":"4","author":"Rosenthal","year":"1990","journal-title":"Growth Factors"},{"key":"10.1074\/jbc.270.13.7717_bib8","doi-asserted-by":"crossref","first-page":"20017","DOI":"10.1016\/S0021-9258(19)47212-8","volume":"264","author":"Connolly","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.13.7717_bib9","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1096\/fasebj.1.6.3315806","volume":"1","author":"Thomas","year":"1987","journal-title":"FASEB J."},{"key":"10.1074\/jbc.270.13.7717_bib10","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1146\/annurev.bi.58.070189.003043","volume":"58","author":"Burgess","year":"1989","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.270.13.7717_bib11","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1126\/science.2479986","volume":"246","author":"Leung","year":"1989","journal-title":"Science"},{"key":"10.1074\/jbc.270.13.7717_bib12","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1126\/science.2479987","volume":"246","author":"Keck","year":"1989","journal-title":"Science"},{"key":"10.1074\/jbc.270.13.7717_bib13","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/0006-291X(89)92729-0","volume":"165","author":"Tischer","year":"1989","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.270.13.7717_bib14","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1073\/pnas.87.7.2628","volume":"87","author":"Conn","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.13.7717_bib15","doi-asserted-by":"crossref","first-page":"9267","DOI":"10.1073\/pnas.88.20.9267","volume":"88","author":"Maglione","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.13.7717_bib16","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3109\/08977199308991586","volume":"9","author":"Hauser","year":"1993","journal-title":"Growth Factors"},{"key":"10.1074\/jbc.270.13.7717_bib17","doi-asserted-by":"crossref","first-page":"11947","DOI":"10.1016\/S0021-9258(18)99049-6","volume":"266","author":"Tischer","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.13.7717_bib18","first-page":"925","volume":"8","author":"Maglione","year":"1993","journal-title":"Oncogene"},{"key":"10.1074\/jbc.270.13.7717_bib19","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/jcb.240470305","volume":"47","author":"Ferrara","year":"1991","journal-title":"J. Cell. Biochem."},{"key":"10.1074\/jbc.270.13.7717_bib20","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1210\/endo.133.2.7688292","volume":"133","author":"Jakeman","year":"1993","journal-title":"Endocrinology"},{"key":"10.1074\/jbc.270.13.7717_bib21","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/0092-8674(93)90573-9","volume":"72","author":"Millauer","year":"1993","journal-title":"Cell"},{"key":"10.1074\/jbc.270.13.7717_bib22","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1172\/JCI116450","volume":"91","author":"Shweiki","year":"1993","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.270.13.7717_bib23","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/359843a0","volume":"359","author":"Shweiki","year":"1992","journal-title":"Nature"},{"key":"10.1074\/jbc.270.13.7717_bib24","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1006\/bbrc.1993.2144","volume":"195","author":"Ladoux","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.270.13.7717_bib25","doi-asserted-by":"crossref","first-page":"4355","DOI":"10.1016\/S0021-9258(17)41787-X","volume":"269","author":"Goldberg","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.13.7717_bib26","first-page":"I-542","volume":"88","author":"Banai","year":"1993","journal-title":"Circulation"},{"key":"10.1074\/jbc.270.13.7717_bib27","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3109\/08977199209011017","volume":"6","author":"Fallon","year":"1992","journal-title":"Growth Factors"},{"key":"10.1074\/jbc.270.13.7717_bib28","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1074\/jbc.270.13.7717_bib29","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1073\/pnas.81.2.357","volume":"81","author":"Thomas","year":"1984","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.13.7717_bib30","doi-asserted-by":"crossref","first-page":"6409","DOI":"10.1073\/pnas.82.19.6409","volume":"82","author":"Thomas","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.13.7717_bib31","doi-asserted-by":"crossref","first-page":"8998","DOI":"10.1073\/pnas.85.23.8998","volume":"85","author":"Frohman","year":"1988","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.13.7717_bib32","doi-asserted-by":"crossref","first-page":"5463","DOI":"10.1073\/pnas.74.12.5463","volume":"74","author":"Sanger","year":"1977","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.13.7717_bib33","doi-asserted-by":"crossref","first-page":"4683","DOI":"10.1093\/nar\/14.11.4683","volume":"14","author":"von Heijne","year":"1986","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.270.13.7717_bib34","doi-asserted-by":"crossref","first-page":"25646","DOI":"10.1016\/S0021-9258(18)47298-5","volume":"269","author":"Park","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.13.7717_bib35","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1006\/bbrc.1994.1705","volume":"201","author":"Kendall","year":"1994","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.270.13.7717_bib36","doi-asserted-by":"crossref","first-page":"10705","DOI":"10.1073\/pnas.90.22.10705","volume":"90","author":"Kendall","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.13.7717_bib37","doi-asserted-by":"crossref","first-page":"16493","DOI":"10.1016\/S0021-9258(18)37619-1","volume":"263","author":"Hammacher","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.13.7717_bib38","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1002\/j.1460-2075.1984.tb02241.x","volume":"3","author":"Stroobant","year":"1984","journal-title":"EMBO J."},{"key":"10.1074\/jbc.270.13.7717_bib39","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1016\/S0021-9258(18)53739-X","volume":"268","author":"Fretto","year":"1993","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818718188?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818718188?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.270.13.7717","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,10]],"date-time":"2021-05-10T02:46:23Z","timestamp":1620614783000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925818718188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,3]]},"references-count":39,"journal-issue":{"issue":"13","published-print":{"date-parts":[[1995,3]]}},"alternative-id":["S0021925818718188"],"URL":"https:\/\/doi.org\/10.1074\/jbc.270.13.7717","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1995,3]]}}}