{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T06:55:07Z","timestamp":1770965707792,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"31","license":[{"start":{"date-parts":[[1995,8,1]],"date-time":"1995-08-01T00:00:00Z","timestamp":807235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T00:00:00Z","timestamp":1604966400000},"content-version":"vor","delay-in-days":9233,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1995,8]]},"DOI":"10.1074\/jbc.270.31.18626","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:56:15Z","timestamp":1027695375000},"page":"18626-18630","source":"Crossref","is-referenced-by-count":60,"title":["Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen"],"prefix":"10.1016","volume":"270","author":[{"given":"Jianmin","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill C.","family":"Milne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. John","family":"Collier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.270.31.18626_bib1","series-title":"Bacterial Toxin and Cell Membranes","first-page":"291","author":"Gill","year":"1978"},{"key":"10.1074\/jbc.270.31.18626_bib2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1146\/annurev.bi.46.070177.000441","volume":"46","author":"Pappenheimer","year":"1977","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.270.31.18626_bib3","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1146\/annurev.pa.26.040186.002235","volume":"26","author":"Simpson","year":"1986","journal-title":"Ann. Rev. Pharmacol. Toxicol."},{"key":"10.1074\/jbc.270.31.18626_bib4","series-title":"Sourcebook of Bacterial Protein Toxins","first-page":"277","author":"Leppla","year":"1991"},{"key":"10.1074\/jbc.270.31.18626_bib5","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.1073\/pnas.79.10.3162","volume":"79","author":"Leppla","year":"1982","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.31.18626_bib6","doi-asserted-by":"crossref","first-page":"10198","DOI":"10.1073\/pnas.90.21.10198","volume":"90","author":"Hanna","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.31.18626_bib7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF03403527","volume":"1","author":"Hanna","year":"1994","journal-title":"Mol. Medicine"},{"key":"10.1074\/jbc.270.31.18626_bib8","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1111\/j.1365-2958.1994.tb00500.x","volume":"13","author":"Klimpel","year":"1994","journal-title":"Mol. Microbiol."},{"key":"10.1074\/jbc.270.31.18626_bib9","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1128\/iai.59.10.3381-3386.1991","volume":"59","author":"Escuyer","year":"1991","journal-title":"Infect. Immun."},{"key":"10.1074\/jbc.270.31.18626_bib10","doi-asserted-by":"crossref","first-page":"10277","DOI":"10.1073\/pnas.89.21.10277","volume":"89","author":"Klimpel","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.31.18626_bib11","doi-asserted-by":"crossref","first-page":"16396","DOI":"10.1016\/S0021-9258(18)42016-9","volume":"267","author":"Molly","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.31.18626_bib12","doi-asserted-by":"crossref","first-page":"7123","DOI":"10.1016\/S0021-9258(17)38364-3","volume":"261","author":"Friedlander","year":"1986","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.31.18626_bib13","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1128\/iai.56.5.1066-1069.1988","volume":"56","author":"Gordon","year":"1988","journal-title":"Infect. Immun."},{"key":"10.1074\/jbc.270.31.18626_bib14","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1073\/pnas.86.7.2209","volume":"86","author":"Blaustein","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.31.18626_bib15","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1111\/j.1365-2958.1991.tb00796.x","volume":"5","author":"Koehler","year":"1991","journal-title":"Mol. Microbiol."},{"key":"10.1074\/jbc.270.31.18626_bib16","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1111\/j.1365-2958.1993.tb00936.x","volume":"10","author":"Milne","year":"1993","journal-title":"Mol. Microbiol."},{"key":"10.1074\/jbc.270.31.18626_bib17","doi-asserted-by":"crossref","first-page":"19103","DOI":"10.1016\/S0021-9258(19)47273-6","volume":"264","author":"Singh","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.31.18626_bib18","doi-asserted-by":"crossref","first-page":"20607","DOI":"10.1016\/S0021-9258(17)32036-7","volume":"269","author":"Milne","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.31.18626_bib19","first-page":"189","volume":"17","author":"Leppla","year":"1984","journal-title":"Adv. Cyclic Nucleotides Protein Phosphorylation Res."},{"key":"10.1074\/jbc.270.31.18626_bib20","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0378-1119(88)90439-8","volume":"69","author":"Welkos","year":"1988","journal-title":"Gene (Amst.)"},{"key":"10.1074\/jbc.270.31.18626_bib21","doi-asserted-by":"crossref","first-page":"5155","DOI":"10.1021\/bi00183a019","volume":"33","author":"Blanke","year":"1994","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.270.31.18626_bib22","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0300-483X(94)90153-8","volume":"87","author":"Finkelstein","year":"1994","journal-title":"Toxicology"},{"key":"10.1074\/jbc.270.31.18626_bib23","doi-asserted-by":"crossref","first-page":"20124","DOI":"10.1016\/S0021-9258(18)54899-7","volume":"266","author":"Quinn","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.31.18626_bib24","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1128\/mr.48.3.199-221.1984","volume":"48","author":"Middlebrook","year":"1984","journal-title":"Microbiol. Rev."},{"key":"10.1074\/jbc.270.31.18626_bib25","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0968-0004(91)90090-I","volume":"16","author":"Ojcius","year":"1991","journal-title":"Trends Biochem. Sci."},{"key":"10.1074\/jbc.270.31.18626_bib26","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1073\/pnas.82.6.1692","volume":"82","author":"Hoch","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.31.18626_bib27","doi-asserted-by":"crossref","first-page":"4950","DOI":"10.1073\/pnas.78.8.4950","volume":"78","author":"Kagan","year":"1981","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.31.18626_bib28","doi-asserted-by":"crossref","first-page":"7614","DOI":"10.1073\/pnas.79.24.7614","volume":"79","author":"Boquet","year":"1982","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.31.18626_bib29","doi-asserted-by":"crossref","first-page":"2872","DOI":"10.1021\/bi00358a020","volume":"25","author":"Donovan","year":"1986","journal-title":"Biochemistry"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925817463538?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925817463538?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.270.31.18626","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,18]],"date-time":"2021-12-18T05:41:22Z","timestamp":1639806082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925817463538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,8]]},"references-count":29,"journal-issue":{"issue":"31","published-print":{"date-parts":[[1995,8]]}},"alternative-id":["S0021925817463538"],"URL":"https:\/\/doi.org\/10.1074\/jbc.270.31.18626","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1995,8]]}}}