{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:15:40Z","timestamp":1790856940475,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"44","license":[{"start":{"date-parts":[[1995,11,1]],"date-time":"1995-11-01T00:00:00Z","timestamp":815184000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,7]],"date-time":"2020-11-07T00:00:00Z","timestamp":1604707200000},"content-version":"vor","delay-in-days":9138,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1995,11]]},"DOI":"10.1074\/jbc.270.44.26037","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T15:07:05Z","timestamp":1027696025000},"page":"26037-26040","source":"Crossref","is-referenced-by-count":116,"title":["Constitutive Activation of Fibroblast Growth Factor Receptor-2 by a Point Mutation Associated with Crouzon Syndrome"],"prefix":"10.1016","volume":"270","author":[{"given":"Karen M.","family":"Neilson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert E.","family":"Friesel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.270.44.26037_bib1","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1146\/annurev.bi.58.070189.003043","volume":"58","author":"Burgess","year":"1989","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.270.44.26037_bib2","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S0960-9822(95)00102-3","volume":"5","author":"Wilkie","year":"1995","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.270.44.26037_bib3","first-page":"1","volume":"60","author":"Johnson","year":"1993","journal-title":"Adv. Cancer Res."},{"key":"10.1074\/jbc.270.44.26037_bib4","doi-asserted-by":"crossref","first-page":"4627","DOI":"10.1128\/MCB.11.9.4627","volume":"11","author":"Johnson","year":"1991","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.270.44.26037_bib5","doi-asserted-by":"crossref","first-page":"11620","DOI":"10.1016\/S0021-9258(19)78170-8","volume":"269","author":"Chellaiah","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26037_bib6","doi-asserted-by":"crossref","first-page":"7899","DOI":"10.1016\/S0021-9258(18)53042-8","volume":"268","author":"Zimmer","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26037_bib7","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1073\/pnas.91.3.989","volume":"91","author":"Cheon","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.44.26037_bib8","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1073\/pnas.89.1.246","volume":"89","author":"Miki","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.44.26037_bib9","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1242\/dev.113.4.1419","volume":"113","author":"Orr-Urtreger","year":"1991","journal-title":"Development"},{"key":"10.1074\/jbc.270.44.26037_bib10","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1242\/dev.116.4.1051","volume":"116","author":"Friesel","year":"1992","journal-title":"Development"},{"key":"10.1074\/jbc.270.44.26037_bib11","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/dvg.1020150205","volume":"15","author":"McDonald","year":"1994","journal-title":"Dev. Genet."},{"key":"10.1074\/jbc.270.44.26037_bib12","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0092-8674(91)90616-7","volume":"66","author":"Amaya","year":"1991","journal-title":"Cell"},{"key":"10.1074\/jbc.270.44.26037_bib13","doi-asserted-by":"crossref","first-page":"3296","DOI":"10.1002\/j.1460-2075.1994.tb06631.x","volume":"13","author":"Peters","year":"1994","journal-title":"EMBO J."},{"key":"10.1074\/jbc.270.44.26037_bib14","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1002\/j.1460-2075.1993.tb05924.x","volume":"12","author":"Werner","year":"1993","journal-title":"EMBO J."},{"key":"10.1074\/jbc.270.44.26037_bib15","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1101\/gad.8.24.3032","volume":"8","author":"Yamaguchi","year":"1994","journal-title":"Genes & Dev."},{"key":"10.1074\/jbc.270.44.26037_bib16","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.1101\/gad.8.24.3045","volume":"8","author":"Deng","year":"1994","journal-title":"Genes & Dev."},{"key":"10.1074\/jbc.270.44.26037_bib17","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/ng0994-98","volume":"8","author":"Reardon","year":"1994","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.270.44.26037_bib18","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/ng0295-173","volume":"9","author":"Rutland","year":"1995","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.270.44.26037_bib19","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/ng1194-275","volume":"8","author":"Jabs","year":"1994","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.270.44.26037_bib20","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1006\/bbrc.1993.1741","volume":"193","author":"Brown","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.270.44.26037_bib21","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1073\/pnas.82.2.488","volume":"82","author":"Kunkel","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.44.26037_bib22","first-page":"76","volume":"1","author":"Moon","year":"1989","journal-title":"Technique (Phila.)"},{"key":"10.1074\/jbc.270.44.26037_bib23","series-title":"Normal Table of Xenopus laevis","author":"Nieuwkoop","year":"1967"},{"key":"10.1074\/jbc.270.44.26037_bib24","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.270.44.26037_bib25","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1073\/pnas.81.7.1991","volume":"81","author":"Church","year":"1984","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.44.26037_bib26","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1128\/MCB.11.5.2481","volume":"11","author":"Friesel","year":"1991","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.270.44.26037_bib27","series-title":"Xenopus laevis: Practical Uses in Cell and Molecular Biology","author":"Peng","year":"1991"},{"key":"10.1074\/jbc.270.44.26037_bib28","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1128\/MCB.9.5.1857","volume":"9","author":"Friesel","year":"1989","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.270.44.26037_bib29","doi-asserted-by":"crossref","first-page":"7581","DOI":"10.1016\/S0021-9258(19)57433-6","volume":"261","author":"Friesel","year":"1986","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26037_bib30","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1242\/dev.118.2.477","volume":"118","author":"Amaya","year":"1993","journal-title":"Development"},{"key":"10.1074\/jbc.270.44.26037_bib31","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/ng0295-165","volume":"9","author":"Wilkie","year":"1995","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.270.44.26037_bib32","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1242\/dev.108.1.173","volume":"108","author":"Green","year":"1990","journal-title":"Development"},{"key":"10.1074\/jbc.270.44.26037_bib33","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/357252a0","volume":"357","author":"Whitman","year":"1992","journal-title":"Nature"},{"key":"10.1074\/jbc.270.44.26037_bib34","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/0092-8674(93)90143-E","volume":"73","author":"MacNicol","year":"1993","journal-title":"Cell"},{"key":"10.1074\/jbc.270.44.26037_bib35","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0092-8674(91)90573-H","volume":"67","author":"Smith","year":"1991","journal-title":"Cell"},{"key":"10.1074\/jbc.270.44.26037_bib36","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0092-8674(87)90110-3","volume":"51","author":"Kimelman","year":"1987","journal-title":"Cell"},{"key":"10.1074\/jbc.270.44.26037_bib37","doi-asserted-by":"crossref","first-page":"9752","DOI":"10.1016\/S0021-9258(17)36947-8","volume":"269","author":"Sorokin","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26037_bib38","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.1128\/MCB.14.6.3535","volume":"14","author":"Watowich","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.270.44.26037_bib39","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1126\/science.7824936","volume":"267","author":"Santoro","year":"1995","journal-title":"Science"},{"key":"10.1074\/jbc.270.44.26037_bib40","doi-asserted-by":"crossref","first-page":"17804","DOI":"10.1016\/S0021-9258(19)37115-7","volume":"267","author":"Hou","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26037_bib41","doi-asserted-by":"crossref","first-page":"6259","DOI":"10.1016\/S0021-9258(17)37362-3","volume":"269","author":"Dawid","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26037_bib42","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1016\/S0021-9258(18)45969-8","volume":"267","author":"Ueno","year":"1992","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818924361?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818924361?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.270.44.26037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T16:13:04Z","timestamp":1621181584000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925818924361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,11]]},"references-count":42,"journal-issue":{"issue":"44","published-print":{"date-parts":[[1995,11]]}},"alternative-id":["S0021925818924361"],"URL":"https:\/\/doi.org\/10.1074\/jbc.270.44.26037","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1995,11]]}}}