{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:20:52Z","timestamp":1791159652374,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"44","license":[{"start":{"date-parts":[[1995,11,1]],"date-time":"1995-11-01T00:00:00Z","timestamp":815184000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,7]],"date-time":"2020-11-07T00:00:00Z","timestamp":1604707200000},"content-version":"vor","delay-in-days":9138,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1995,11]]},"DOI":"10.1074\/jbc.270.44.26382","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:53:54Z","timestamp":1027695234000},"page":"26382-26390","source":"Crossref","is-referenced-by-count":147,"title":["Biochemical, Structural, and Transglutaminase Substrate Properties Of Human Loricrin, the Major Epidermal Cornified Cell Envelope Protein"],"prefix":"10.1016","volume":"270","author":[{"given":"Eleonora","family":"Candi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerry","family":"Melino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampiero","family":"Mei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edit","family":"Tarcsa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo-Il","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyuben N.","family":"Marekov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter M.","family":"Steinert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.270.44.26382_bib1","series-title":"Intermediate Filament Structure","author":"Parry","year":"1995"},{"key":"10.1074\/jbc.270.44.26382_bib2","doi-asserted-by":"crossref","first-page":"19S","DOI":"10.1038\/jid.1994.5","volume":"103","author":"Steinert","year":"1994","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.270.44.26382_bib3","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1146\/annurev.bi.63.070194.002021","volume":"63","author":"Fuchs","year":"1994","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.270.44.26382_bib4","series-title":"Molecular Biology of the Skin","first-page":"107","author":"Reichert","year":"1993"},{"key":"10.1074\/jbc.270.44.26382_bib5","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/1523-1747.ep12472288","volume":"100","author":"Eckert","year":"1993","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.270.44.26382_bib6","doi-asserted-by":"crossref","first-page":"6626","DOI":"10.1016\/S0021-9258(18)38163-8","volume":"266","author":"Hohl","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26382_bib7","doi-asserted-by":"crossref","first-page":"17702","DOI":"10.1074\/jbc.270.30.17702","volume":"270","author":"Steinert","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26382_bib8","first-page":"33","volume":"2","author":"Steinert","year":"1995","journal-title":"Cell Death Differ."},{"key":"10.1074\/jbc.270.44.26382_bib9","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1242\/jcs.107.2.693","volume":"107","author":"Steven","year":"1994","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.270.44.26382_bib10","doi-asserted-by":"crossref","first-page":"18060","DOI":"10.1016\/S0021-9258(19)37152-2","volume":"267","author":"Yoneda","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26382_bib11","first-page":"663","volume":"24","author":"Shvets","year":"1990","journal-title":"Mol. Biol. (Mosc.)"},{"key":"10.1074\/jbc.270.44.26382_bib12","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1006\/geno.1994.1522","volume":"23","author":"Rothnagel","year":"1994","journal-title":"Genomics"},{"key":"10.1074\/jbc.270.44.26382_bib13","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/0141-8130(91)90037-U","volume":"13","author":"Steinert","year":"1991","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1074\/jbc.270.44.26382_bib14","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/0092-8674(90)90073-N","volume":"60","author":"Mehrel","year":"1990","journal-title":"Cell"},{"key":"10.1074\/jbc.270.44.26382_bib15","first-page":"578","volume":"92","author":"Thacher","year":"1989","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.270.44.26382_bib16","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/1523-1747.ep12499806","volume":"98","author":"Michel","year":"1992","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.270.44.26382_bib17","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/1523-1747.ep12612769","volume":"104","author":"Kim","year":"1995","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.270.44.26382_bib18","doi-asserted-by":"crossref","first-page":"18026","DOI":"10.1074\/jbc.270.30.18026","volume":"270","author":"Kim","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26382_bib19","doi-asserted-by":"crossref","first-page":"21971","DOI":"10.1016\/S0021-9258(18)45834-6","volume":"265","author":"Kim","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26382_bib20","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1083\/jcb.47.3.593","volume":"47","author":"Matoltsy","year":"1970","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.270.44.26382_bib21","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/1047-8477(90)90071-J","volume":"104","author":"Steven","year":"1990","journal-title":"J. Struct. Biol."},{"key":"10.1074\/jbc.270.44.26382_bib22","doi-asserted-by":"crossref","first-page":"27979","DOI":"10.1016\/S0021-9258(18)46883-4","volume":"269","author":"Kim","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26382_bib23","first-page":"329","volume":"52","author":"Hibino","year":"1988","journal-title":"Agric. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26382_bib24","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1006\/jmbi.1994.1714","volume":"244","author":"de Smit","year":"1994","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.270.44.26382_bib25","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0076-6879(85)13049-1","volume":"113","author":"Folk","year":"1985","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.270.44.26382_bib26","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/0304-4165(80)90002-1","volume":"630","author":"Milhaud","year":"1980","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.270.44.26382_bib27","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0021-9258(18)63316-2","volume":"245","author":"Chung","year":"1970","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.270.44.26382_bib28","doi-asserted-by":"crossref","first-page":"5664","DOI":"10.1021\/bi00592a022","volume":"18","author":"Steinert","year":"1979","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.270.44.26382_bib29","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1083\/jcb.101.4.1257","volume":"101","author":"Dale","year":"1983","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.270.44.26382_bib30","series-title":"The Biology of the Skin and Hair Growth","first-page":"291","author":"Matoltsy","year":"1965"},{"key":"10.1074\/jbc.270.44.26382_bib31","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1135\/cccc19712012","volume":"36","author":"Fric","year":"1971","journal-title":"Collect. Czech. Chem. Commun."},{"key":"10.1074\/jbc.270.44.26382_bib32","doi-asserted-by":"crossref","first-page":"5418","DOI":"10.1021\/bi00415a006","volume":"27","author":"Mack","year":"1988","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.270.44.26382_bib33","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/198188a0","volume":"198","author":"Walsh","year":"1963","journal-title":"Nature"},{"key":"10.1074\/jbc.270.44.26382_bib34","doi-asserted-by":"crossref","first-page":"8472","DOI":"10.1073\/pnas.87.21.8472","volume":"87","author":"Parameswaran","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.270.44.26382_bib35","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1432-1033.1994.tb18681.x","volume":"220","author":"Groenen","year":"1994","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.270.44.26382_bib36","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/0092-8674(85)90216-8","volume":"40","author":"Simon","year":"1985","journal-title":"Cell"},{"key":"10.1074\/jbc.270.44.26382_bib37","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1001\/archderm.1985.01660040061013","volume":"121","author":"Williams","year":"1985","journal-title":"Arch. Dermatol."},{"key":"10.1074\/jbc.270.44.26382_bib38","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1001\/archderm.1993.01680260088013","volume":"129","author":"Hohl","year":"1993","journal-title":"Arch. Dermatol."},{"key":"10.1074\/jbc.270.44.26382_bib39","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1001\/archderm.131.3.363","volume":"131","author":"Lavrijsen","year":"1995","journal-title":"Arch. Dermatol."},{"key":"10.1074\/jbc.270.44.26382_bib40","first-page":"1146","volume":"55","author":"Russell","year":"1994","journal-title":"Am. J. Human Genet."},{"key":"10.1074\/jbc.270.44.26382_bib41","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1126\/science.7824952","volume":"276","author":"Huber","year":"1995","journal-title":"Science"},{"key":"10.1074\/jbc.270.44.26382_bib42","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/ng0395-279","volume":"9","author":"Russell","year":"1995","journal-title":"Nature Genet."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818924907?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818924907?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.270.44.26382","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,2]],"date-time":"2022-01-02T07:30:21Z","timestamp":1641108621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925818924907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,11]]},"references-count":42,"journal-issue":{"issue":"44","published-print":{"date-parts":[[1995,11]]}},"alternative-id":["S0021925818924907"],"URL":"https:\/\/doi.org\/10.1074\/jbc.270.44.26382","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1995,11]]}}}