{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:53:00Z","timestamp":1790265180239,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"32","license":[{"start":{"date-parts":[[1996,8,1]],"date-time":"1996-08-01T00:00:00Z","timestamp":838857600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"vor","delay-in-days":8840,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1996,8]]},"DOI":"10.1074\/jbc.271.32.19402","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:50:28Z","timestamp":1027695028000},"page":"19402-19408","source":"Crossref","is-referenced-by-count":112,"title":["prk, a Cytokine-inducible Human Protein Serine\/Threonine Kinase Whose Expression Appears to be Down-regulated in Lung Carcinomas"],"prefix":"10.1016","volume":"271","author":[{"given":"Bo","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiqi","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter T.","family":"Reissmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis J.","family":"Slamon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Arceci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luo","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.271.32.19402_bib1","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/0092-8674(94)90543-6","volume":"79","author":"Hunter","year":"1994","journal-title":"Cell"},{"key":"10.1074\/jbc.271.32.19402_bib2","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1182\/blood.V86.3.841.841","volume":"86","author":"Hirama","year":"1995","journal-title":"Blood"},{"key":"10.1074\/jbc.271.32.19402_bib3","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1126\/science.271.5247.353","volume":"271","author":"Walworth","year":"1996","journal-title":"Science"},{"key":"10.1074\/jbc.271.32.19402_bib4","first-page":"4164","volume":"12","author":"Simmon","year":"1992","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.271.32.19402_bib5","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/363637a0","volume":"363","author":"Fenton","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.271.32.19402_bib6","first-page":"4445","volume":"13","author":"Kitada","year":"1993","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.271.32.19402_bib7","first-page":"249","volume":"5","author":"Hamanaka","year":"1994","journal-title":"Cell Growth & Differ."},{"key":"10.1074\/jbc.271.32.19402_bib8","doi-asserted-by":"crossref","first-page":"4882","DOI":"10.1073\/pnas.90.11.4882","volume":"90","author":"Clay","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.271.32.19402_bib9","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1242\/jcs.107.6.1509","volume":"107","author":"Golsteyn","year":"1994","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.271.32.19402_bib10","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1083\/jcb.129.6.1617","volume":"129","author":"Golsteyn","year":"1995","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.271.32.19402_bib11","doi-asserted-by":"crossref","first-page":"10351","DOI":"10.1074\/jbc.270.17.10351","volume":"270","author":"Donohue","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.271.32.19402_bib12","first-page":"2097","volume":"9","author":"Grana","year":"1994","journal-title":"Oncogene"},{"key":"10.1074\/jbc.271.32.19402_bib13","series-title":"Molecular Cloning: A Laboratory Manual","first-page":"2.64","author":"Sambrook","year":"1989"},{"key":"10.1074\/jbc.271.32.19402_bib14","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0021-9258(19)57397-5","volume":"263","author":"Caplen","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.271.32.19402_bib15","first-page":"975","volume":"9","author":"Dai","year":"1994","journal-title":"Oncogene"},{"key":"10.1074\/jbc.271.32.19402_bib16","doi-asserted-by":"crossref","first-page":"30848","DOI":"10.1016\/S0021-9258(18)47359-0","volume":"269","author":"Cheng","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.271.32.19402_bib17","first-page":"1257","volume":"9","author":"Cheng","year":"1995","journal-title":"Leukemia"},{"key":"10.1074\/jbc.271.32.19402_bib18","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1126\/science.3291115","volume":"241","author":"Hanks","year":"1988","journal-title":"Science"},{"key":"10.1074\/jbc.271.32.19402_bib19","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1126\/science.2814487","volume":"246","author":"Malter","year":"1989","journal-title":"Science"},{"key":"10.1074\/jbc.271.32.19402_bib20","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1146\/annurev.bi.62.070193.002321","volume":"62","author":"Fantl","year":"1993","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.271.32.19402_bib21","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1056\/NEJM199402033300507","volume":"330","author":"Cline","year":"1994","journal-title":"N. Engl. J. Med."},{"key":"10.1074\/jbc.271.32.19402_bib22","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1128\/jb.115.3.966-974.1973","volume":"115","author":"Hartwell","year":"1973","journal-title":"J. Bacteriol."},{"key":"10.1074\/jbc.271.32.19402_bib23","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1093\/genetics\/96.4.859","volume":"96","author":"Schild","year":"1980","journal-title":"Genetics"},{"key":"10.1074\/jbc.271.32.19402_bib24","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/1056-8719(94)90075-2","volume":"31","author":"Kurosawa","year":"1994","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1074\/jbc.271.32.19402_bib25","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1182\/blood.V86.1.294.bloodjournal861294","volume":"86","author":"Wilhide","year":"1995","journal-title":"Blood"},{"key":"10.1074\/jbc.271.32.19402_bib26","first-page":"1261","volume":"5","author":"Levin","year":"1995","journal-title":"Oncogene"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819843788?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819843788?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.271.32.19402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T01:36:48Z","timestamp":1641260208000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819843788"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,8]]},"references-count":26,"journal-issue":{"issue":"32","published-print":{"date-parts":[[1996,8]]}},"alternative-id":["S0021925819843788"],"URL":"https:\/\/doi.org\/10.1074\/jbc.271.32.19402","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1996,8]]}}}