{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:32:09Z","timestamp":1783038729575,"version":"3.54.6"},"reference-count":43,"publisher":"Elsevier BV","issue":"46","license":[{"start":{"date-parts":[[1996,11,1]],"date-time":"1996-11-01T00:00:00Z","timestamp":846806400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T00:00:00Z","timestamp":1602720000000},"content-version":"vor","delay-in-days":8749,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1996,11]]},"DOI":"10.1074\/jbc.271.46.28772","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T15:14:15Z","timestamp":1027696455000},"page":"28772-28776","source":"Crossref","is-referenced-by-count":124,"title":["Isolation of a NCK-associated Kinase, PRK2, an SH3-binding Protein and Potential Effector of Rho Protein Signaling"],"prefix":"10.1016","volume":"271","author":[{"given":"Lawrence A.","family":"Quilliam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Que T.","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leigh A.","family":"Mickelson-Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John K.","family":"Westwick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew B.","family":"Sparks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian K.","family":"Kay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy A.","family":"Jenkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debra J.","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal G.","family":"Copeland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Channing J.","family":"Der","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.271.46.28772_bib1","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/373573a0","volume":"373","author":"Pawson","year":"1995","journal-title":"Nature"},{"key":"10.1074\/jbc.271.46.28772_bib2","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/0092-8674(94)90367-0","volume":"76","author":"Yu","year":"1994","journal-title":"Cell"},{"key":"10.1074\/jbc.271.46.28772_bib3","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1073\/pnas.93.4.1540","volume":"93","author":"Sparks","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.271.46.28772_bib4","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/bies.950170507","volume":"17","author":"Quilliam","year":"1995","journal-title":"Bioessays"},{"key":"10.1074\/jbc.271.46.28772_bib5","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1093\/nar\/18.4.1048","volume":"18","author":"Lehmann","year":"1990","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.271.46.28772_bib6","doi-asserted-by":"crossref","first-page":"11713","DOI":"10.1073\/pnas.90.24.11713","volume":"90","author":"Lee","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.271.46.28772_bib7","first-page":"5824","volume":"12","author":"Li","year":"1992","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.271.46.28772_bib8","doi-asserted-by":"crossref","first-page":"6729","DOI":"10.1074\/jbc.270.12.6729","volume":"270","author":"Guo","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.271.46.28772_bib9","doi-asserted-by":"crossref","first-page":"17363","DOI":"10.1016\/S0021-9258(17)32443-2","volume":"269","author":"Rivero-Lezcano","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.271.46.28772_bib10","doi-asserted-by":"crossref","first-page":"20242","DOI":"10.1074\/jbc.270.35.20242","volume":"270","author":"Galisteo","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.271.46.28772_bib11","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1128\/MCB.15.3.1169","volume":"15","author":"Hu","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.271.46.28772_bib12","doi-asserted-by":"crossref","first-page":"3571","DOI":"10.1128\/MCB.15.7.3571","volume":"15","author":"Meisner","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.271.46.28772_bib13","first-page":"5500","volume":"13","author":"Suen","year":"1993","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.271.46.28772_bib14","first-page":"5834","volume":"12","author":"Chou","year":"1992","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.271.46.28772_bib15","doi-asserted-by":"crossref","first-page":"7359","DOI":"10.1074\/jbc.270.13.7359","volume":"270","author":"Chou","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.271.46.28772_bib16","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/0092-8674(94)90528-2","volume":"78","author":"Derry","year":"1994","journal-title":"Cell"},{"key":"10.1074\/jbc.271.46.28772_bib17","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1006\/bbrc.1994.1313","volume":"199","author":"Mukai","year":"1994","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.271.46.28772_bib18","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1432-1033.1995.tb20395.x","volume":"227","author":"Palmer","year":"1995","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.271.46.28772_bib19","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1126\/science.271.5249.645","volume":"271","author":"Watanabe","year":"1996","journal-title":"Science"},{"key":"10.1074\/jbc.271.46.28772_bib20","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1126\/science.271.5249.648","volume":"271","author":"Amano","year":"1996","journal-title":"Science"},{"key":"10.1074\/jbc.271.46.28772_bib21","doi-asserted-by":"crossref","first-page":"22731","DOI":"10.1074\/jbc.270.39.22731","volume":"270","author":"Bagrodia","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.271.46.28772_bib22","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0092-8674(00)81050-8","volume":"84","author":"Symons","year":"1996","journal-title":"Cell"},{"key":"10.1074\/jbc.271.46.28772_bib23","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/0092-8674(84)90440-9","volume":"37","author":"Cepko","year":"1984","journal-title":"Cell"},{"key":"10.1074\/jbc.271.46.28772_bib24","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0092-8674(90)90589-7","volume":"60","author":"Tanaka","year":"1990","journal-title":"Cell"},{"key":"10.1074\/jbc.271.46.28772_bib25","first-page":"5016","volume":"11","author":"O'Bryan","year":"1991","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.271.46.28772_bib26","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1073\/pnas.88.4.1247","volume":"88","author":"Strathmann","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.271.46.28772_bib27","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0168-9525(91)90085-5","volume":"7","author":"Copeland","year":"1991","journal-title":"Trends Genet."},{"key":"10.1074\/jbc.271.46.28772_bib28","series-title":"Genetics and Probability in Animal Breeding Experiments","first-page":"77","author":"Green","year":"1981"},{"key":"10.1074\/jbc.271.46.28772_bib29","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1006\/geno.1994.1212","volume":"20","author":"Hamel","year":"1994","journal-title":"Genomics"},{"key":"10.1074\/jbc.271.46.28772_bib30","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1128\/jvi.43.1.26-36.1982","volume":"43","author":"Jenkins","year":"1982","journal-title":"J. Virol."},{"key":"10.1074\/jbc.271.46.28772_bib31","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/S0076-6879(95)55037-2","volume":"255","author":"Westwick","year":"1995","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.271.46.28772_bib32","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0092-8674(05)80020-0","volume":"81","author":"Hill","year":"1995","journal-title":"Cell"},{"key":"10.1074\/jbc.271.46.28772_bib33","first-page":"2913","volume":"9","author":"Galang","year":"1994","journal-title":"Oncogene"},{"key":"10.1074\/jbc.271.46.28772_bib34","doi-asserted-by":"crossref","first-page":"8512","DOI":"10.1073\/pnas.91.18.8512","volume":"91","author":"Quilliam","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.271.46.28772_bib35","doi-asserted-by":"crossref","first-page":"5725","DOI":"10.1128\/MCB.15.10.5725","volume":"15","author":"Rivero-Lezcano","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.271.46.28772_bib36","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1182\/blood.V87.7.2621.bloodjournal8772621","volume":"87","author":"Remold-O'Donnell","year":"1996","journal-title":"Blood"},{"key":"10.1074\/jbc.271.46.28772_bib37","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0960-9822(02)00423-2","volume":"6","author":"Aspenstrom","year":"1996","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.271.46.28772_bib38","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1093\/oxfordjournals.jhered.a111221","volume":"83","author":"Lane","year":"1992","journal-title":"J. Hered."},{"key":"10.1074\/jbc.271.46.28772_bib39","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/oxfordjournals.jhered.a108252","volume":"63","author":"Lane","year":"1972","journal-title":"J. Hered."},{"key":"10.1074\/jbc.271.46.28772_bib40","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1126\/science.7618083","volume":"269","author":"Knaus","year":"1995","journal-title":"Science"},{"key":"10.1074\/jbc.271.46.28772_bib41","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0968-0004(96)10022-0","volume":"21","author":"Symons","year":"1996","journal-title":"Trends Biochem. Sci."},{"key":"10.1074\/jbc.271.46.28772_bib42","doi-asserted-by":"crossref","first-page":"9193","DOI":"10.1074\/jbc.271.16.9193","volume":"271","author":"Kamada","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.271.46.28772_bib43","author":"Huff","year":"1997","journal-title":"Oncogene"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818349949?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818349949?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.271.46.28772","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T21:47:47Z","timestamp":1639691267000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925818349949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,11]]},"references-count":43,"journal-issue":{"issue":"46","published-print":{"date-parts":[[1996,11]]}},"alternative-id":["S0021925818349949"],"URL":"https:\/\/doi.org\/10.1074\/jbc.271.46.28772","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1996,11]]}}}